Is Advil Or Tylenol Better For A Fever?

Is Advil Or Tylenol Better For A Fever? Official Answer. Tylenol (acetaminophen) is only effective at relieving pain and fever, but Advil (ibuprofen) relieves inflammation in addition to pain and fever. Other differences: Some research suggests NSAIDs such as Advil are more effective than Tylenol at relieving pain. What is the best fever reducer? Acetaminophen,