What Happens If You Eat Grapefruit While Taking Methadone?
What Happens If You Eat Grapefruit While Taking Methadone? Exposure to substances like grapefruit juice, that inhibit these isoenzymes may result in increased blood levels of methadone, and thus may manifest clinically as unexpected opioid toxicity. Can you drink grapefruit juice while on methadone? Grapefruit juice can increase the blood levels and effects of methadone.