Can Proin Cause Kidney Failure In Dogs?

by | Last updated on January 24, 2024

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Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported . In some cases, death, including euthanasia, has been reported.

Is there an alternative to Proin for dogs?

A new and often successful alternative to prescription medications such as Proin or Stilbestrol for the management and control of urinary in dogs is the use of hydraulic urethral occluders .

What are the side effects of Proin for dogs?

  • Loss of appetite.
  • Vomiting and diarrhea.
  • Heavy drooling.
  • Restlessness and irritability.
  • Increased blood pressure or heart rate.
  • Seizures.
  • Difficulty urinating.

Will Proin hurt my dog?

Havoc should be absolutely fine after ingesting the Proin tablet ! He ingested approximately 4.4 mg/kg (milligrams per kilogram of body weight), and more serious signs of toxicity usually occur with doses over 15 mg/kg.

Is Proin safe for dogs with kidney disease?

Phenylpropanolamine should not be used in pets than are allergic to it or in pregnant pets. It should be used cautiously in pets with glaucoma, seizures, enlarged prostate, elevated thyroid hormone, diabetes mellitus, heart or vessel disorders, kidney disease, or high blood pressure .

Is too much Proin bad for dogs?

While safe at therapeutic doses, when the chewable form is accidentally ingested in large amounts, it can result in severe poisoning . Clinical signs of high blood pressure, abnormal heart rate, dilated pupils, tremors, agitation, and even seizures can be seen. Prompt veterinary attention is required with any overdose.

Is Proin safe?

PROIN ® may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insufficiency, diabetes, glaucoma, and other conditions associated with high blood pressure.

Can Proin make incontinence worse?

In the case of accidental ingestion by humans, contact a physician immediately. Contact your veterinarian if you notice restlessness or irritability, loss of appetite, the incontinence persists or worsens , or any other unusual signs. Consult your veterinarian before using PROIN with any other medications.

Is Proin an estrogen?

The estrogen product (Incurin) increases the number and sensitivity of alpha receptors, whereas the phenylpropanolamine (Proin) directly stimulates the alpha receptors ,” she says.

What helps incontinence in dogs naturally?

  • Phytoestrogens. There are plant derived estrogens used to treat spay-related incontinence. ...
  • Corn Silk. Some people use corn silk both as a supportive treatment and as a remedy. ...
  • Saw Palmetto. This herb works as anti-inflammatory. ...
  • Sang Piao Xiao San. ...
  • Acupuncture.

How can I help my old dog with incontinence?

At-Home Solutions for Dog Incontinence

Things you can do to help your dog include limiting her water late at night (but only if this won’t interfere with other health conditions!) and adding extra walks to try and empty the bladder. If it is difficult to get your dog outside, consider using pee pads in the house.

Is phenylpropanolamine safe for dogs?

Phenylpropanolamine has an excellent bioavailability for both controlled-release and immediate-release formulations (93.7% and 98%, respectively) in dogs .

What medications can cause urinary incontinence in dogs?

Some medications can cause excessive urine dilution and therefore urinary incontinence. The most common medication that results in urinary incontinence is prednisone . Prednisone is a common medication that has anti-inflammatory and immunosuppressive actions and is widely used.

Can you cut Proin in half?

Do not split or crush ... The recommended dosage is 2 to 4 mg/kg (0.9 to 1.8 mg/lb) of body weight once daily according to Table 1 below. Administer PROIN ER with food (see Clinical Pharmacology). Do not split or crush tablets.

How often should I give my dog Proin?

A typical dosage of Proin for treating incontinence in dogs is 0.91 mg/lb every 12 hours , but up to 22.7 mg/lb every 8 hours may be recommended for urethral sphincter hypotonus. When the medicine is used to treat retrograde ejaculation a range of 1.4 – 1.8 mg/lb may be used instead.

James Park
Author
James Park
Dr. James Park is a medical doctor and health expert with a focus on disease prevention and wellness. He has written several publications on nutrition and fitness, and has been featured in various health magazines. Dr. Park's evidence-based approach to health will help you make informed decisions about your well-being.