Does mercaptopurine cause fever? Mercaptopurine-induced fever has been reported in patients with acute lymphocytic leukemia and IBD though uncommon .
What are the side effects of mercaptopurine?
- Black, tarry stools.
- clay colored stools.
- cough or hoarseness.
- decreased appetite.
- fever or chills.
- nausea, vomiting.
- pinpoint red spots on the skin.
- rash, itchy skin.
Can mercaptopurine make you sick?
Side effects from azathioprine and mercaptopurine may include the following: Nausea (feeling sick), vomiting and loss of appetite . This reaction can be especially strong during the first few weeks of treatment.
What happens if you take too much mercaptopurine?
Does mercaptopurine weaken the immune system?
MERCAPTOPURINE, 6-MP (mer kap toe PYOOR een) is a chemotherapy drug. It interferes with the growth of cancer cells and can reduce immune system activity .
Does mercaptopurine make you tired?
Possible Side Effects (More Common)
This may raise your risk of infection, make you tired and weak (fatigue) , and raise your risk of bleeding. Soreness of the mouth and throat may happen with high doses of this drug.
What are the side effects of 6-MP?
- This medication belongs to a class of drugs called immunomodulators. ...
- Infrequently reported side effects may include headache, nausea, vomiting, diarrhea, tiredness, mouth sores, rash, fever, joint pain, low blood counts and anemia, and liver inflammation.
Can you take ibuprofen with mercaptopurine?
Interactions between your drugs
No interactions were found between ibuprofen and mercaptopurine . However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
When is the best time to take mercaptopurine?
You can take Mercaptopurine with food or on an empty stomach but the choice of method should be consistent from day to day. You should take your medicine at least 1 hour before or 2 hours after having milk or dairy products .
How long can you stay on mercaptopurine?
Research suggests that the effectiveness of azathioprine and mercaptopurine does not diminish over time . While guidelines state that stopping treatment may be considered after four years for patients remaining in remission, many experts now believe thiopurine treatment should be continued indefinitely.
Does mercaptopurine cause night sweats?
Tell your doctor if you experience any of the following symptoms: stomach pain; fever; unexplained weight loss; night sweats or easy bruising or bleeding. Talk to your doctor about the risks of taking this medication. Mercaptopurine may cause other side effects.
What happens if you take mercaptopurine with milk?
Taking mercaptopurine liquid
But whichever you choose, you should do the same thing each day. You should drink some water after taking the liquid. Milk and dairy products can make this drug less effective so you should take Xaluprine at least 1 hour before or 2 hours after milk or dairy products.
What is mercaptopurine 50 mg used for?
This medication is used to treat a certain type of cancer (acute lymphocytic leukemia) . It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells. Talk to the doctor about the risks and benefits of mercaptopurine, especially when used by children and young adults.
What does mercaptopurine do for ulcerative colitis?
The most common symptoms of ulcerative colitis are bloody diarrhoea and abdominal pain. Azathioprine and 6-mercaptopurine are thought to reduce inflammation by blocking the immune system .
What does mercaptopurine do for Crohn’s disease?
Mercaptopurine works to reduce inflammation in the body by targeting the immune system . 6MP is given at a lower dose than azathioprine. It may take up to 6 months for the 6MP to start working effectively. Your doctor may want you to continue taking other medicines during this time to help manage your disease.
How common is hair loss with mercaptopurine?
Side effects included leukopenia (11.2%), abnormal liver function tests (3.8%), various infections, including pneumonia (3.1%), pancreatitis (2.5%), nausea (2.1%), headache (2.8%), fever (1.4%), hair loss ( 1%) , and rash (0.7%).
Can you drink alcohol on mercaptopurine?
Can I drink alcohol while I am taking mercaptopurine? Yes, it safe to drink alcohol while you are taking mercaptopurine, however large quantities of alcohol should be avoided .
Does mercaptopurine make you gain weight?
Can you take mercaptopurine with prednisone?
Is 6-mercaptopurine the same as mercaptopurine?
Mercaptopurine (6-MP), sold under the brand name Purinethol among others , is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn’s disease, and ulcerative colitis.
Can mercaptopurine cause pancreatitis?
6-Mercaptopurine (6-MP) has an important role in the treatment of inflammatory bowel disease. Its most frequent short-term complication has proven to be pancreatitis , which we have now seen in 13 of 400 (3.25%) patients (12 Crohn’s disease, 1 ulcerative colitis) and which we here describe.
Can I take Tylenol with mercaptopurine?
Interactions between your drugs
No interactions were found between mercaptopurine and Tylenol . However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Can you take antihistamines with mercaptopurine?
Can you take Tylenol with 6-MP?
You may take acetaminophen (Tylenol®) tablets . Ask your health care team about the right dose for you. Talk to your health care team first before starting ibuprofen (Advil®, Motrin®), naproxen (Aleve®) or aspirin (acetylsalicylic acid, ASA), since these may increase your chance of bleeding.
How safe is mercaptopurine?
This medicine may increase your risk of getting certain types of cancer, including skin cancer and cervical cancer . Some teenagers and young adults with Crohn’s disease or ulcerative colitis developed a rare type of cancer called hepatosplenic T-cell lymphoma (HSTCL).
Can mercaptopurine cause liver damage?
Mercaptopurine can also lead to a distinctive acute, clinically apparent liver injury that usually presents with fatigue and jaundice and a cholestatic or mixed pattern of serum enzyme elevations 1 to 6 months after starting therapy, but sometimes later, particularly following an increase in dose.
Does mercaptopurine cause lymphoma?
Can you eat grapefruit with mercaptopurine?
You should avoid the regular consumption of large amounts of grapefruits and grapefruit juice while taking budesonide . Grapefruit can raise the levels of budesonide in your body and lead to increased side effects.
Can mercaptopurine cause hair loss?
Can mercaptopurine be taken with food?
How long can you stay on mercaptopurine?
Research suggests that the effectiveness of azathioprine and mercaptopurine does not diminish over time . While guidelines state that stopping treatment may be considered after four years for patients remaining in remission, many experts now believe thiopurine treatment should be continued indefinitely.
Is mercaptopurine a chemo drug?
What is mercaptopurine prescribed for?
Mercaptopurine is used alone or with other chemotherapy drugs to treat acute lymphocytic leukemia (ALL; also called acute lymphoblastic leukemia and acute lymphatic leukemia; a type of cancer that begins in the white blood cells). Mercaptopurine is in a class of medications called purine antagonists.
Can mercaptopurine cause weight gain?
Swelling of the body, tiredness, bruising. High blood pressure which may cause headaches, dizziness, blurred vision. Belly pain. Increased appetite and weight gain .
