Adults and teenagers—The usual dose is 5 to 15 mg, injected into a muscle or under the skin, one or two times a day . Children—The usual dose is 5 to 10 mg, injected into a muscle or under the skin, one or two times a day.
How is vitamin K administered newborn?
Since 1961, the American Academy of Pediatrics (AAP) has recommended that a single 0.5 mg to 1.0 mg dose of vitamin K be administered intramuscularly (IM) to all newborns shortly after birth to prevent VKDB.
How do you administer IV vitamin K?
If phytonadione is to administered intravenously, dilute in 50 ml of normal saline or dextrose solution and administer over 60 minutes. Monitor vital signs every 15 minutes x 4, then every 30 minutes x 2. IV phytonadione is never given IV push.
When do you administer vitamin K to INR?
Vitamin K given orally is more effective than subcutaneous vitamin K injection, and as effective as intravenous administration when INR values are compared 24 hours after administration . A 1.0-mg vitamin K dose is likely most appropriate for patients with INR values between 4.5 and 10.
Is vitamin K subcutaneous or intramuscular injection?
Vitamin K is available in injectable and oral formulations. According to the product's labeling, vitamin K solution for injection can be administered intravenously, intramuscularly, and subcutaneously with higher preference for the subcutaneous route due to the risk of anaphylaxis with the intravenous route.
Where should vitamin K be injected?
This medication is given by injection under the skin or into a muscle or vein as directed by your doctor . If this medication is given into a vein, it should be injected very slowly (no more than 1 milligram per minute) to reduce the risk of serious side effects.
Can Vit K be given IM?
Therefore, SC injection of vitamin K is not recommended. Intramuscular (IM) injection of vitamin K should never be used . Efficacy data are lacking, and patients with high INR values are at risk of hematoma formation at the injection site.
Can parents refuse vitamin K?
Vitamin K deficiency bleeding (VKDB) is a preventable coagulopathy, but some parents refuse this service , and this has resulted in cases of (VKDB).
Can vitamin K be given orally to newborns?
Can Vitamin K be given orally? Vitamin K can be given to babies as a liquid by mouth. However, it is less effective as the absorption of the whole drug cannot be guaranteed.
What type of vitamin K is given to newborns?
Accordingly, it is recommended that vitamin K1 should be given as a single intramuscular dose of 0.5 mg (for babies weighing 1,500 g or less at birth) or 1.0 mg (for babies weighing more than 1,500 g at birth) to all neonates within the first 6 hours after birth following initial stabilisation of the baby and an ...
How quickly does IV vitamin K work?
Intravenous vitamin K is necessary (to permit the synthesis of new, functional clotting proteins) but not sufficient; a large dose (5–10 mg administered intravenously) will normalize the INR in most patients, but its effect will take 24 hours to be fully manifest.
How much vitamin K is safe?
How much vitamin K do I need? Adults need approximately 1 microgram a day of vitamin K for each kilogram of their body weight . For example, someone who weighs 65kg would need 65 micrograms a day of vitamin K, while a person who weighs 75kg would need 75 micrograms a day.
What happens with too much vitamin K?
The effects of vitamin K toxicity can include jaundice in newborns , hemolytic anemia, and hyperbilirubinemia. Toxicity also blocks the effects of oral anticoagulants.
Does vitamin K have side effects?
Most people do not experience any side effects when taking vitamin K in the recommended amount each day. But some people may have an upset stomach or diarrhea. When applied to the skin: Vitamin K1 is POSSIBLY SAFE for most people when applied as a cream that contains 0.1% vitamin K1.
Is vitamin K used to stop bleeding?
Vitamin K is used to prevent and treat certain blood clotting (coagulation) issues. It's also used to prevent severe bleeding (hemorrhagic disease) in newborns. Vitamin K may be used in cases of ongoing IV feeding. It may also be used when antibiotics have killed bacteria in the intestines that make vitamin K.
