Do not eat or drink grapefruit or grapefruit juice while you’re taking this medicine. Grapefruit can increase the concentration of nifedipine in your body and make side effects worse. If you’re taking nifedipine as a liquid, it will usually be made up for you by your pharmacist.
How does consumption of grapefruit or grapefruit juice affect nifedipine?
Grapefruit juice is known to increase the oral bioavailability of dihydropyridine calcium channel blockers , including nifedipine, by reducing presystemic clearance.
How does grapefruit affect calcium channel blockers?
They’re used as part of the treatment of conditions such as high blood pressure (hypertension) and coronary heart disease. Grapefruit juice interacts with some calcium channel blockers and increases the level of the medicine in your blood .
Does grapefruit interfere with blood pressure medicine?
Though grapefruit does not interfere with most blood pressure medications , it can cause a few medications to overcorrect blood pressure.
Can you take nifedipine with citrus juice?
Grapefruits and grapefruit juice may increase the effects of nifedipine by increasing the amount of this medicine in your body. You should not eat grapefruit or drink grapefruit juice while you taking this medicine.
What meds should not be taken with grapefruit?
Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).
What blood pressure meds should not be taken with grapefruit?
- Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin).
- Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).
Why is grapefruit bad for high blood pressure?
Grapefruit contains compounds that may interfere with how your body absorbs some drugs , including some blood pressure medicines. It can leave too much or too little of the drug in your bloodstream, which may be dangerous. Always ask your doctor or pharmacist if grapefruit could affect the medicine you’re taking.
How long should you wait to eat grapefruit after taking medication?
This makes it more likely that you will have side effects from the medicine. Interactions can happen up to three days after eating or drinking grapefruit. This means you cannot drink grapefruit juice in the morning and take your medications later in the day to stop possible medicine interactions.
Why is nifedipine no longer used?
If it continues for a long time, the heart and arteries may not function properly . This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.
When should you not take nifedipine?
Stop taking nifedipine and tell a doctor straight away if you get: yellow skin or the whites of your eyes turn yellow – these can be signs of liver problems. chest pain that is new or worse – this side effect needs to be checked out as chest pain is a possible symptom of a heart attack.
Is it OK to take nifedipine at bedtime?
Moreover, bedtime administration of nifedipine GITS reduced the incidence of edema as an adverse event by 91%, and the total number of all adverse events by 74% as compared to morning dosing (p=0.026).
Can I eat grapefruit in the morning and take Lipitor at night?
How much grapefruit is okay when taking statins like Lipitor? To be on the safe side, many researchers suggest you avoid consuming grapefruit entirely when taking statins such as Lipitor .
Does grapefruit make you poop?
Citrus fruits like oranges, grapefruits, and mandarins are high in fiber and contain several compounds that can reduce constipation, including pectin and naringenin.
Which medicines should not be taken together?
- Dangerous duo: Tylenol and multi-symptom cold medicines. ...
- Dangerous duo: Any combo of ibuprofen, naproxen, and aspirin. ...
- Dangerous duo: Antihistamines and motion-sickness medications. ...
- Dangerous duo: Anti-diarrheal medicine and calcium supplements. ...
- Dangerous duo: St.
