Topamax (topiramate) stays in your system between four and six days after your last dose, depending on your personal factors such as dosage and metabolism.
Does topiramate cause permanent brain damage?
An open study examined the behavioral and cognitive effects of topiramate as add-on treatment in children and adolescents with mild to severe mental retardation [Coppola et al. 2008]. The authors reported a significant cognitive deterioration in about 70% of patients at 3 months, persisting in about 20% at 12 months.
Does Topamax brain fog go away?
Patients often experience brain fog, or a decrease in cognition, when beginning Topamax. Some report an inability to quickly process information, language problems, or think clearly. For some, this symptom resolves as the body acclimates to dosing .
Does Topamax cause memory loss?
Can Topamax cause permanent memory loss? Topamax may be associated with dementia and should be used with caution in older patients. Still, it has not been well established that Topamax can cause permanent memory loss .
How long does it take for your body to get used to Topamax?
It may take 8 to 12 weeks for you to see the full effect of Topamax (topiramate) on your migraine headaches. In clinical studies, some people had fewer headaches after 4 weeks of treatment. Treatment with Topamax for migraine prevention is taken daily and is usually started slowly at lower doses.
Do you gain weight back after stopping Topamax?
Conclusions: Loss of body weight is a reversible effect, which at 6 months after TPM discontinuation shows a clear trend to return to baseline values. HOMA-IR is the only predictive factor of weight regain .
Can Topamax cause personality change?
Topamax can sometimes cause personality changes that affect the way people behave, react, feel, or interact with others. For example, the drug may cause agitation, aggression, or other behavior problems. Topamax may also cause mood changes, such as anxiety, mood swings, and depression.
Is Topamax linked to dementia?
Older patients have greater susceptibility to side effects, especially neurotoxic effects because of altered pharmacokinetics and impaired homeostatic mechanisms. We suggest that topiramate should be included in the list of drugs associated with dementia , and it should be used with caution in older patients.
Is there a recall on Topamax?
The recall includes Topamax with NDC code 50458-641-65 and lot numbers OKG110 with an expiration date of 06-2012 and OLG222 with an expiration date of 09-2012. The recall stems from four consumer reports of an uncharacteristic odor thought to be caused by TBA .
How do you feel on Topamax?
- tingling of the arms and legs (paresthesia)
- not feeling hungry.
- weight loss.
- speech problems.
- fatigue.
- dizziness or sleepiness.
- slow reactions (psychomotor slowing)
- nervousness.
What does Topamax do to your brain?
Topiramate works by reducing the spread of seizure activity in the brain and restoring the normal balance of nerve activity . For epilepsy – brain cells normally “talk” to each other using electrical signals and chemicals. Seizures can happen when the brain cells are not working properly or working faster than normal.
Can I stop 25 mg Topamax cold turkey?
Never stop taking Topamax suddenly, or “cold turkey”, because this may cause you to have an increased risk of seizures, more frequent seizures, or other serious withdrawal symptoms. This can happen even if you do not take Topamax for epilepsy.
Do you need to wean off Topamax?
There are no reports of bad reactions to suddenly stopping use of Topiramate, so there is no need to wean off the drug . On the other hand, the entire class of anticonvulsants is known to lead to seizures if you stop taking them suddenly.
Does Topamax make you pee a lot?
Can topiramate (Topamax) make me urinate more often? The medication itself won't make you urinate more often . However, it's recommended to drink plenty of liquids when taking topiramate (Topamax) to prevent kidney stones. Drinking more water may cause you to urinate more often.
What is the average weight loss on Topamax?
The mean dose of topiramate was 195 mg/day (range, 100–375 mg/day). All patients lost a substantial amount of weight on topiramate. The average weight loss was 22 lb (10 kg; range, 8–56 lb [4–25 kg]) . No patient discontinued topiramate because of side effects.
