According to the Natural Medicines Database, methylcobalamin, also known as Methyl B12, is considered likely safe when used appropriately . However, high doses of this vitamin may cause adverse effects.
What are the side effects of methylcobalamin?
- Nausea.
- Vomiting.
- Diarrhea.
- Loss of appetite.
- Headache.
How much B12 methylcobalamin should I take daily?
The recommended daily amount of vitamin B-12 for adults is 2.4 micrograms .
Who should not take methylcobalamin?
You should not use methylcobalamin if you are allergic to vitamin B12 or cobalt . Tell your doctor if you have ever had: Leber's disease or other form of optic nerve damage; an iron or folic acid deficiency; or.
Can I take methylcobalamin daily?
Dosage. For the best bioavailability and absorption, the recommended dose is 500 mcg three times daily or 1500 mcg daily of methylcobalamin or 5-adenosylcobalamin. Most generic vitamins contain cyanocobalamin, which may not be as effective or as beneficial.
Does methylcobalamin cause weight gain?
Despite the numerous processes in which vitamin B12 is involved, there's little evidence to suggest that it has any influence on weight gain or loss .
What does methylcobalamin do in the body?
Methylcobalamin is an active form of vitamin B 12 that helps in synthesis of methionine and S-adenosylmethionine . It is required for integrity of myelin, neuronal function, proper red blood cell formation and DNA synthesis.
What is Methylcobalamin B12 good for?
Methylcobalamin is used to treat vitamin B12 deficiency . Vitamin B12 is important for the brain and nerves, and for the production of red blood cells. Methylcobalamin is sometimes used in people with pernicious anemia, diabetes, and other conditions.
Is it OK to take 1000 mcg B12 daily?
The recommended dose for treating vitamin B12 deficiency is 1000 mcg daily. The recommended dose for preventing vitamin B12 deficiency is 1500 mg or 2500 mcg (sublingual tablets) daily.
Can vitamin B12 damage your liver?
The common forms of vitamin B include vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine) and B12 (cyanocobalamin). Except for niacin (when given in high doses), there is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice.
How long does methylcobalamin stay in your system?
Generally speaking, around 50 to 98% of the vitamin B12 taken is excreted from the body 48 hours after injection . Other studies have shown that vitamin B12 has a half-life of around six days in the blood, which means that it would take six days before half of the administered amount is excreted from the body.
Is methylcobalamin a painkiller?
Recently several lines of evidence demonstrated that MeCbl may have potential analgesic effects in experimental and clinical studies. For example, MeCbl alleviated pain behaviors in diabetic neuropathy, low back pain and neuralgia.
What is the difference between vitamin B12 and methylcobalamin?
Cyanocobalamin is a synthetic form of vitamin B12 found only in supplements, while methylcobalamin is a naturally occurring form that you can get through either food sources or supplements.
When is the best time to take vitamin B12?
“Take water-soluble vitamins on an empty stomach with a glass of water,” recommends Dr. Perez-Gallardo. And since it can be energizing, Dr. Perez-Gallardo says that the best time to take vitamin B12 is in the morning , so it won't affect your sleep.
How much methylcobalamin should I inject?
How much is given: Your doctor will tell you how much Methylcobalamin Injection will need to be given and for how long it is to be given. This is determined by many factors including your body weight and your medical condition. The usual dose is 10 mg by slow intramuscular injection .
How do you know if your B12 is low?
- Weakness, tiredness, or lightheadedness.
- Heart palpitations and shortness of breath.
- Pale skin.
- A smooth tongue.
- Constipation, diarrhea, loss of appetite, or gas.
- Nerve problems like numbness or tingling, muscle weakness, and problems walking.
- Vision loss.
