Can You Take Topamax With Antidepressants?

Can You Take Topamax With Antidepressants? Can you take Topamax with antidepressants? The study found that the participants taking Topamax in addition to their prescribed depression medication significantly improved depressed mood, suicidality, insomnia, agitation, and anxiety symptoms compared to those taking a placebo. What should you not take with Topamax? Valproic acid (brand name examples: