Target organs include the bone marrow, skin, and nervous system after either acute or chronic excessive exposure.
What is a target organ chemical?
Target organ toxins are chemicals that can cause adverse effects or disease states manifested in specific organs of the body. Toxins do not affect all organs in the body to the same extent due to their different cell structures.
What are target organs?
target organ. A tissue or organ upon which a hormone exerts its action ; generally, a tissue or organ with appropriate receptors for a hormone.
What is target organ for a hormone?
| Endocrine gland/ source of hormone Hormone Target organ or tissue | Anterior pituitary (adenohypophysis) ACTH (adrenocorticotrophic hormone) Adrenal cortex | FSH (follicle stimulating hormone) Ovaries / testes (tubules) | LH (luteinizing hormone) Ovaries / testes (Leydig cells) | GH (growth hormone) All tissues |
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What is target tissue in biology?
Definition: The biological tissue(s) most adversely affected by exposure to a chemical substance .
What are target organs of hypertension?
The heart, kidney, brain, and arterial blood vessels are prime targets of hypertensive damage. Uncontrolled hypertension accelerates the damage to these organs and results in eventual organ failure and cardiovascular death and disability.
What is a hormone *?
A hormone is a chemical that is made by specialist cells , usually within an endocrine gland, and it is released into the bloodstream to send a message to another part of the body. It is often referred to as a ‘chemical messenger’.
What is a target organ effect?
Target organ effects indicate which bodily organs are most likely to be affected by exposure to a substance . ... Specific target organ toxicity – single exposure, (STOT-SE) means specific, non-lethal target organ toxicity arising from a single exposure to a chemical. This is an example of an acute effect.
What is the most common target organ of toxicity?
The liver is the primary site for the metabolism of many chemicals and drugs by the body and is also the primary site of potential toxic injury (hepatotoxicity). Like all organs, the liver is composed of various cell types; predominately hepatocytes.
What does Stot stand for?
Let’s start with the abbreviation: STOT stands for specific target organ toxicity . Target organ toxicity is divided into two substance classifications. SE for single exposure and RE for repeated exposure.
What is the target organ of melatonin?
The suprachiasmatic nucleus appears as a major target of melatonin in mammals. The pineal hormone may thus be involved in a feedback loop of the mammalian photoneuroendocrine system.
What is target site in human body?
The target site is the tissue or organ on which the enzyme or hormone acts . For example, the follicle stimulating harmone secreted by the pituitary targets the ovary in females and the testis in males. The enzymes do not cause any effect on tissues or organs other than the target site.
What are the 7 hormones?
The anterior pituitary produces seven hormones. These are the growth hormone (GH), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), beta endorphin, and prolactin .
What is a target tissue in the endocrine system?
Target tissue refers to the intended site that a hormone will affect such as muscle. Receptor site. Receptor sites are special sites located on every target tissue and only communicate with the specific hormone intended for the target tissue.
What is a target tissue quizlet?
Target tissue. A group of cells that have receptors embedded in the plasma membrane that are complementary in shape to specific hormone molecules . Only these cells will respond to the specific hormone.
What does hypersecretion mean?
Hypersecretion is when an excess of one or more hormone is secreted from a gland . Hyposecretion is when the amount of hormones are released is too low.
