What Is Combination Therapy In Hypertension?

by | Last updated on January 24, 2024

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Combination therapy provides greater antihypertensive power than the use of high doses of monotherapy, adding several mechanisms of action that block various pathways of increased blood pressure, in addition to providing greater protection to target organs than monotherapy, and reduced potential for side effects.

What combination of drugs are prescribed to treat hypertension?

Drug Brand name Amlodipine and benazepril (2.5 mg/10 mg, 5 mg/10 mg, 5 mg/20 mg) Lotrel Diltiazem and enalapril (180 mg/5 mg) Teczem Felodipine and enalapril (5 mg/5 mg) Lexxel Verapamil and trandolapril (180 mg/2 mg, 240 mg/1 mg, 240 mg/2 mg, 240 mg/4 mg) Tarka

Why do we use combination therapy?

Combination therapy has been shown to dramatically reduce the likelihood of drug resistance (many drug-resistant mutations are mutually exclusive) and to suppress viral replication to the point that progression to AIDS is significantly slowed.

What is the best therapy for hypertension?

Diuretics are often recommended as the first line of therapy for most people who have high blood pressure. However, your doctor may start a medicine other than a diuretic as the first line of therapy if you have certain medical problems. For example, ACE inhibitors are often a choice for people with diabetes.

What is first line treatment for hypertension?

The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.

Is 150 90 A good blood pressure?

high blood pressure is considered to be 140/90mmHg or higher (or 150/90mmHg or higher if you’re over the age of 80) ideal blood pressure is usually considered to be between 90/60mmHg and 120 /80mmHg.

How can I bring my blood pressure down immediately?

  1. Exercise most days of the week. Exercise is the most effective way to lower your blood pressure. ...
  2. Consume a low-sodium diet. Too much sodium (or salt) causes blood pressure to rise. ...
  3. Limit alcohol intake to no more than 1 to 2 drinks per day. ...
  4. Make stress reduction a priority.

Why Antibiotics are given in combination?

Combination therapy is mostly practiced because of one or more of the following reasons: Broadening antibacterial spectrum . Use of more than one agent broadens the antibacterial spectrum of the empirical therapy and thus ensures that at least one agent will cover the infecting organism.

What is the second line treatment of TB?

Grouping of drugs Drugs line category Group 1 Isoniazid, rifampicin, ethambutol, pyrazinamide Second-line anti-tuberculosis drugs Group 2 Moxifloxacin, high dose levofloxacin (fluoroquinolones) Group 3 Linezolid, delamanid, bedaquiline (newer drugs with increased evidence)

How does combination antiretroviral therapy work?

Treatment that uses a combination of three or more drugs to treat HIV infection. Combination antiretroviral therapy stops the virus from making copies of itself in the body . This may lessen the damage to the immune system caused by HIV and may slow down the development of AIDS.

What are 3 ways to treat hypertension?

  1. Lose extra pounds and watch your waistline. ...
  2. Exercise regularly. ...
  3. Eat a healthy diet. ...
  4. Reduce sodium in your diet. ...
  5. Limit the amount of alcohol you drink. ...
  6. Quit smoking. ...
  7. Cut back on caffeine. ...
  8. Reduce your stress.

What food is bad for high blood pressure?

  • Salt or sodium. ...
  • Deli meat. ...
  • Frozen pizza. ...
  • Pickles. ...
  • Canned soups. ...
  • Canned tomato products. ...
  • Sugar. ...
  • Processed foods with trans or saturated fat.

What is the latest treatment for high blood pressure?

This drug, nicknamed the “triple pill” by the investigators, combines low doses of three existing drugs for blood pressure. Namely, these are: telmisartan (20 milligrams), amlodipine (2.5 milligrams), and chlorthalidone (12.5 milligrams).

What is the safest hypertension medicine?

Safe medications to use include methyldopa and potentially some diuretics and beta-blockers, including labetalol.

What are two treatments for hypertension?

  • Diuretics. Diuretics, sometimes called water pills, are medications that help your kidneys eliminate sodium and water from the body. ...
  • Angiotensin-converting enzyme (ACE) inhibitors. ...
  • Angiotensin II receptor blockers (ARBs). ...
  • Calcium channel blockers.

Which agents are preferred for the initial treatment of hypertension?

Thiazide diuretics , angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and calcium channel blockers are the preferred medications in nonblack patients; thiazide diuretics and calcium channel blockers are preferred in black patients.

Sophia Kim
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Sophia Kim
Sophia Kim is a food writer with a passion for cooking and entertaining. She has worked in various restaurants and catering companies, and has written for several food publications. Sophia's expertise in cooking and entertaining will help you create memorable meals and events.