What Is PUJ Obstruction Kidney? - Fixanswer

Treatment. Most cases of UPJ obstruction actually do not require surgery and resolve on their own. However, if patients exhibit pain, recurrent infections, evidence of worsening function or increasing swelling, they may require a surgery called a pyeloplasty to prevent kidney injury and correct the blockage.

How common is PUJ obstruction?

How common is ureteropelvic (UPJ) junction obstruction? UPJ obstruction occurs in about one of every 1,500 births , and is responsible for about 80% of all swollen urine-collecting systems. Males are affected at more than double the rate of females, and the left kidney is affected about twice as often as the right.

Is PUJ obstruction hereditary?

Hereditary hydronephrosis (MIM 143400) is an autosomal dominant trait that causes unilateral or bilateral pelvi-ureteric junction (PUJ) obstruction. Linkage analysis was undertaken in 5 families with hereditary PUJ obstruction using the major histocompatibility complex locus as a test marker.

Is PUJ obstruction serious?

Because the obstruction is affected by blood flow the problem might stop and start, depending on how much blood is going through the vessel. PUJ obstruction can cause pain , repeated urine infections and damage to the affected kidney, but often there are no symptoms at all.

How do you get rid of a PUJ obstruction?

A pyeloplasty is a surgical procedure that is indicated for a pelviureteric junction (PUJ) obstruction. The PUJ is the portion of the collecting system that connects the renal pelvis to the ureter. The standard treatment for pelviureteric junction obstruction is open pyeloplasty.

Is a kidney blockage serious?

Severe cases of urinary blockage and hydronephrosis can damage the kidneys and lead to kidney failure . If kidney failure occurs, treatment will be needed with either dialysis or a kidney transplant. However, most people can recover from hydronephrosis if treated promptly.

Is PUJ obstruction kidney disease?

PUJ obstruction is most often a congenital condition , occurring in 1 in 1500 births. It tends to affect the left kidney more than the right, but in 10% of cases it affects both kidneys.

Can hydronephrosis go away on its own?

Although surgery is sometimes needed, hydronephrosis often resolves on its own . Mild to moderate hydronephrosis. Your doctor may opt for a wait-and-see approach to see if you get better on your own. Even so, your doctor may recommend preventive antibiotic therapy to lower the risk of urinary tract infections.

Is UPJ obstruction painful?

UPJ obstruction may also cause pain without an infection . Some cases of UPJ obstruction are not clear. Urine may drain normally at times, and at other times be blocked. This causes pain that comes and goes.

Can UPJ obstruction cause high blood pressure?

Hypertension is an incompletely understood complication of UPJ obstruction. Animal and human models have implicated the renin–angiotensin system, oxidative stress, nitric oxide dysregu- lation and renal sympathetic nerve activity in its pathogenesis.

How long is UPJ obstruction surgery?

The typical length of the operation is three to four hours . The surgery is performed through three small (1 cm) incisions made in the abdomen.

Is hydronephrosis a birth defect?

Birth defects in the urinary tract may cause hydronephrosis. Even when birth defects are the cause, hydronephrosis may be mild and may improve as the child gets older. However, birth defects may also cause hydronephrosis that is severe or gets worse over time.

Is hydronephrosis a kidney disease?

Hydronephrosis (kidney swelling) occurs as the result of a disease . It is not a disease itself. Conditions that may lead to hydronephrosis include: Blockage of a ureter due to scarring caused by prior infections, surgeries, or radiation treatments.

How long does it take for hydronephrosis to go away?

Kidney function will begin decreasing almost immediately with the onset of hydronephrosis but is reversible if the swelling resolves. Usually kidneys recover well even if there is an obstruction lasting up to 6 weeks .