Salvia (Salvia divinorum) is an herb in the mint family found in southern Mexico. The main active ingredient in salvia, salvinorin A
What is the active chemical in Salvia divinorum?
Salvinorin A , the main active ingredient of S. divinorum, inhibited in a nor-binaltorphimine- and naloxone-sensitive manner electrically induced contractions.
What compound is in salvia?
The main active compound present in Salvia divinorum is Salvinorin A , which is the only known non-nitrogenous κ-opioid receptor agonist [72]. Lee et al. [73] isolated several other neoclerodane diterpenoids from salvia, also showing agonistic activity on κ-opioid receptor.
Is sage a hallucinogen?
Diviner’s sage contains a powerful hallucinogen that may someday inspire a new class of depression, pain, and addiction medications.
Is salvinorin A orally active?
| Clinical data | Routes of administration Buccal/Sublingual, Smoked | ATC code none | Legal status |
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Do Salvias come back every year?
Rockin’ and Unplugged salvias are generally considered to be annuals since they are expected to overwinter only in warm climates. People typically plant them in spring, compost them in late fall, and replant the following spring. ... Plant them once and they will return every year .
What is another name for Salvia divinorum?
Other names
In Mexico, the plant is called in Spanish ‘hojas de la pastora’ or ‘ska María pastora’. Common names in English are: Diviner’s Sage, Lady Salvia, Magic Mint , Purple Sticky, Sally D, Sage of the Seers or simply and most widely Salvia.
Is Salvia officinalis hallucinogenic?
Salvia officinalis is the sage with gray-green leaves that is a common culinary seasoning. Salvia divinorum, native to the northern Sierra Mazateca Mountains in Mexico, has hallucinogenic properties when ingested or smoked .
Is Purple sage hallucinogenic?
It is a mild hallucinogen when smoked , and is used in Native American ceremonies and Native American herbal medicine. It is native to the western United States, including Utah, and has been identified as the plant Grey had in mind.
Is burning sage bad for your health?
This is because sage is thought to have antimicrobial properties that help kill bacteria, viruses, and fungi. Keep in mind that burning sage creates smoke , which can cause health problems for individuals who are prone to asthma and other respiratory conditions.
Is salvia a sedative?
It is concluded that Salvia guaranitica extracts and its active principle cirsiliol, possess sedative and hypnotic properties ; cirsiliol produces these effects probably acting on the so-called type I benzodiazepine receptor.
How does salvinorin A affect the brain?
Salvinorin A affects structures in the brain called opioid receptors . This makes salvia different from other hallucinogenic drugs like LSD and mushrooms, which affect the brain’s levels of a chemical called serotonin.
Who discovered salvinorin A?
It was described and named in 1982 by A. Ortega and co-workers . At least 12 similar compounds have been discovered or synthesized, but none are appreciably psychoactive. Unlike most hallucinogens, salvinorin A is a terpenoid, not an alkaloid.
How do I protect my salvias over winter?
Half-hardy perennial salvias can be left in the ground where they have been growing if the soil is not too cold or wet in winter. Cut back the top growth to 15cm and protect the roots and basal buds with a thick layer of manure or bark chippings . Uncover the plants in early spring when the worst of the frosts are over.
Should you cut back salvias?
With July in full flow , now is the perfect time to trim back salvias so they can reward you with flowers throughout summer and autumn.
Do salvias bloom all summer?
These beautiful annuals bloom all summer and well into fall because they tolerate cool temperatures. As an added bonus, sometimes these plants self sow or die back to the ground to return the next summer. ... These annual salvias do best in full sun, but they tolerate light shade and are somewhat drought tolerant.
