Which PHS organization is responsible for monitoring institutional compliance with PHS Policy? The Office of Laboratory Animal Welfare (OLAW, formerly OPRR) .
Which PHS organization is responsible for monitoring institutional compliance with PHS Policy?
The Office of Laboratory Animal Welfare (OLAW) is responsible for monitoring institutional compliance with PHS policy and guidelines.
Who monitors PHS compliance?
The Office for Protection from Research Risks (OPRR) of the National Institutes of Health (NIH) develops, implements, and oversees compliance with the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (1).
Who is responsible for enforcing the PHS Policy?
The PHS Policy has been law since 1985 and is enforced by the Office of Laboratory Animal Welfare (OLAW) of the National Institutes of Health (NIH) .
Which organization at the NIH is charged with ensuring compliance with the PHS Policy?
The IACUC is responsible for oversight of the animal care and use program and its components as described in the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (Policy) and the Guide for the Care and Use of Laboratory Animals (Guide ).
Who benefits from the Iacuc’s activities to ensure compliance?
The IACUC’s activities to ensure compliance benefit whom? The organization, investigators, animals, and public health and welfare .
What are the 3 R’s in animal testing?
The Three Rs stand for reduction, replacement, and refinement . In their book The Principles of Humane Experimental Technique, published in 1959, authors Russell and Burch proposed that all research using animals should be evaluated to see whether the Three Rs could be applied.
Is NSF under PHS?
Agencies with such requirements include the Public Health Service (PHS) and related components such as the National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA)as well as the National Science Foundation (NSF).
Is Barda a PHS agency?
BARDA also participates in the governmental inter-agency Public Health Emergency Medical Countermeasures Enterprise (PHEMCE), providing coordination across the US federal government in developing and deploying such countermeasures.
What is PHS assurance?
Introduction. The Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (Policy) requires that institutions have an OLAW-approved Animal Welfare Assurance before carrying out any activities involving live vertebrate animals.
What does the PHS regulate?
The Public Health Service Policy on the Humane Care and Use of Laboratory Animals. The Public Health Service (PHS) Policy is based on the “ US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research and Teaching ” which were developed by the Interagency Research Animal Committee ...
What are the laws that affect the use of animals in research teaching and testing?
The Animal Welfare Act (AWA) is the federal law governing the care and use of laboratory animals in the United States. ... The PHS Guide for the Care and Use of Laboratory Animals sets the standards for care and housing that must be provided for animals in PHS-funded studies.
Who appoints the members of the Iacuc?
1. The Institutional Official appoints members to standing university research committees and, as authorized by the President, appoints the Chair and members to the IACUC. Approximately once a year, the DRECS submits recommendations for membership to the Institutional Official.
What is the purpose of an Institutional Animal Care and Use Committee?
An institutional animal care and use committee (IACUC) is required by federal regulations for most institutions that use animals in research, teaching, and testing . The IACUC has a key oversight role, including the review and approval of animal use activities, and inspection of animal facilities.
What must Investigators do prior to making any significant changes in their use of animals?
What must investigators do prior to making any significant changes in their use of animals? Obtain IACUC approval . ... Remove the animal from the threat if safe to do so and contact the attending veterinarian or IACUC.
Which of the following actions has the potential to reduce the severity of inflammation following CFA use?
A statistical analysis should be used whenever possible. All of the following would likely reduce the severity of inflammation following CFA use EXCEPT: using multiple smaller volume injection sites instead of fewer larger volume sites. maintaining sterility of the antigen solution before it is mixed with the adjuvant.
