What Does The Rough ER Do?

by | Last updated on January 24, 2024

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The endoplasmic reticulum can either be smooth or rough, and in general its function is

to produce proteins for the rest of the cell to function

. The rough endoplasmic reticulum has on it ribosomes, which are small, round organelles whose function it is to make those proteins.

What are the two main functions of the rough ER?

The rough ER, studded with millions of membrane bound ribosomes, is involved with

the production, folding, quality control and despatch of some proteins

. Smooth ER is largely associated with lipid (fat) manufacture and metabolism and steroid production hormone production. It also has a detoxification function.

What is the main function of RER?

The RER is responsible for

protein synthesis, modification, packaging, and quality control

. We say that the RER makes proteins, but actually most of this is done by the ribosomes attached to its surface. These are called membrane-bound ribosomes. One key point to remember is that the RER makes secretory proteins only.

What is the role of the rough ER in protein synthesis?

Rough ER lies immediately adjacent to the cell nucleus, and its membrane is continuous with the outer membrane of the nuclear envelope. The ribosomes on rough ER specialize in

the synthesis of proteins that possess a signal sequence that directs them specifically to the ER for processing

.

What does rough ER specialize in?

Rough ER lies immediately adjacent to the cell nucleus, and its membrane is continuous with the outer membrane of the nuclear envelope. The ribosomes on rough ER specialize in

the synthesis of proteins that possess a signal sequence

that directs them specifically to the ER for processing.

What is difference between RER and SER Class 9 in points?

The most basic difference between RER and SER is

the presence of ribosomes

. When ribosomes attach to the surface of an ER, it gives a characteristic rough appearance; hence it is called Rough ER. On the other hand, a smooth ER does not have ribosomes on its surface.

What is the difference between SER and RER?

The main difference lies between the SER and RER is

the presence of ribosomes

, as SER do not have ribosomes but RER have ribosomes. SER mainly produce and export lipids and protein and function for detoxification, while RER produces, secrete and export proteins and few hormones.

What is the main function of smooth ER?

The smooth endoplasmic reticulum functions in many metabolic processes. It

synthesizes lipids, phospholipids as in plasma membranes, and steroids

. Cells that secrete these products, such as cells of the testes, ovaries, and skin oil glands, have an excess of smooth endoplasmic reticulum.

What is the function of rough ER Class 9?

Rough Endoplasmic Reticulum Function:

The majority of the functions of rough ER is associated with

protein synthesis

. Rough endoplasmic reticulum also plays a vital role in protein folding. Also ensures quality control (regarding correct protein folding).

What are the four major functions of the endoplasmic reticulum?

The ER is the largest organelle in the cell and is a major site of

protein synthesis and transport, protein folding, lipid and steroid synthesis, carbohydrate metabolism and calcium storage

[1–7].

What is the difference between rough ER and smooth ER?

Both rough ER and smooth ER

have the same types of membranes

but they have different shapes. Rough ER looks like sheets or disks of bumpy membranes while smooth ER looks more like tubes. Rough ER is called rough because it has ribosomes attached to its surface. … Smooth ER (SER) acts as a storage organelle.

Does mRNA go to the rough ER?

First, the cell copies DNA to mRNA during transcription. Then the mRNA is taken to the ribosome where it reads the mRNA and tRNA gets the correct amino acids for the ribosome to put together. … In the rough ER,

the protein is folded and then shipped to the Golgi apparatus

to be distributed to the cell.

Are proteins synthesized in the rough ER?

Proteins are

synthesized on the rough ER

. Those that are processed are inserted cotranslationally into the ER. Such insertion requires the presence of a signal peptide at the N terminus, which is recognized by a specific receptor (docking protein) on the ER membrane.

Which cells would have a lot of rough ER?

Cells that specialize in protein secretion contain large amounts of rough endoplasmic reticulum. For instance,

cells of the pancreas

that produce the protein insulin, have abundant rough endoplasmic reticulum.

Why does the pancreas have a lot of rough ER?

It is generally believed that AP is initiated within acinar cells

1

. … Pancreatic acinar cells are highly specialized for digestive enzyme synthesis, storage, and secretion

17

, therefore they have abundant endoplasmic reticulum (ER)

to meet the protein synthesis rate

, the highest among all adult human tissues

18 – 21

.

Does rough ER have double membrane?

The membrane of the rough endoplasmic reticulum forms

large double-membrane sheets

that are located near, and continuous with, the outer layer of the nuclear envelope.

Charlene Dyck
Author
Charlene Dyck
Charlene is a software developer and technology expert with a degree in computer science. She has worked for major tech companies and has a keen understanding of how computers and electronics work. Sarah is also an advocate for digital privacy and security.