Zoloft (sertraline chloride) is one of the most popular
SSRI antidepressants
on the market. Pfizer developed and marketed Zoloft as a safer alternative with fewer side effects and withdrawal symptoms than competitor drugs such as Eli Lilly’s Prozac.
Is SSRI the same as MAOI?
SSRIs: What’s the difference? Monoamine oxidase inhibitors (MAOIs) and selective serotonin reuptake inhibitors (SSRIs) are types of antidepressants used to treat depression. MAOIs are an older class of antidepressants that are not used as much because of drug and food interactions.
Which drugs are MAOI?
- Isocarboxazid (Marplan)
- Phenelzine (Nardil)
- Selegiline (Emsam)
- Tranylcypromine (Parnate)
What kind of SSRI is Zoloft?
Sertraline is known as
a selective serotonin reuptake inhibitor
(SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.
Is sertraline an MAOI or SSRI?
What is its mechanism of action? Sertraline belongs to a class of drugs called
selective serotonin reuptake inhibitors (SSRIs)
. Other drugs in this class are: fluoxetine (Prozac, Sarafem)
Is 25mg of Zoloft enough for anxiety?
The standard dose of Zoloft for
anxiety
is 25 mg or 50 mg per day. According to the Food and Drug Administration (FDA), these are the standard doses of Zoloft for other disorders: Major depressive disorder: 50 mg daily. OCD: 50 mg per day for those older than 13 years of age.
Why should you not take sertraline on a night?
Many people who experience nausea and other side effects from sertraline opt to take it at night in order to limit these side effects. Since sertraline
can interfere with sleep in a small
percentage of users, many people also opt to take sertraline in the morning.
What is better SSRI or MAOI?
Although SSRIs are the current frontline treatment for depression,
MAOIs
(monoamine oxidase inhibitors) were the first antidepressants developed. They are typically more potent than SSRIs because they affect more neurotransmitters, and they can cause more side effects.
Can you take MAOI and SSRI together?
The use of
SSRIs and SNRIs should be avoided with an MAOI
because of the risk of serious adverse effects and even death. The combination has a high risk of serotonin syndrome, and deaths have been reported when taken at therapeutic doses.
Is Prozac an MAOI or SSRI?
Prozac is the brand name of the drug fluoxetine,
a selective serotonin reuptake inhibitor (SSRI)
. SSRIs are second-generation antidepressants, which means they are newer than first-generation medications such as monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants (TCAs).
Is Xanax considered an MAOI?
Drug | Rasagiline Selegiline Isocarboxazid Phenelzine | Drug Class | Monoamine oxidase inhibitors (MAOIs) | Lexapro | Yes | Xanax | Yes |
---|
What foods should be avoided with MAOIs?
Smoked or processed meats
, such as hot dogs, bologna, bacon, corned beef or smoked fish. Pickled or fermented foods, such as sauerkraut, kimchi, caviar, tofu or pickles. Sauces, such as soy sauce, shrimp sauce, fish sauce, miso and teriyaki sauce.
Is Trazodone a MAOI drug?
Trazodone is chemically unrelated to the selective serotonin reuptake inhibitors (SSRIs), the tricyclic antidepressants (TCAs) or the
monoamine
oxidase inhibitors (MAO inhibitors). It is chemically related to nefazodone (Serzone) and shares its actions.
Why is Zoloft bad for you?
Taking Zoloft may put you
at risk for a rare, possibly life-threatening condition called serotonin syndrome
. This risk is higher if you are also taking other serotonin-related medications like triptans (a common migraine medication), tricyclic antidepressants, or the pain medication Ultram (tramadol).
Is it better to take Zoloft in the morning or at night?
Administer once daily either morning or evening. If Zoloft makes you drowsy,
take it at bedtime
. May be taken with or without food; however, this needs to be consistent. Talk to your doctor if your mood worsens or you experience any suicidal thoughts particularly during the first few months of therapy.
What does Zoloft withdrawal feel like?
Because Zoloft leaves your body so quickly, stopping it too abruptly can cause discontinuation syndrome to develop. Among the symptoms that may be experienced are
nausea, tremor, dizziness, muscle pains, weakness, insomnia, and anxiety
.