Piperazine, also called hexahydropyrazine, anthelmintic drug used in the treatment of
intestinal roundworm infection
in humans and domestic animals (including poultry) and against pinworm
Can people take piperazine?
Adults and teenagers—3.5 grams (piperazine hexahydrate)
per day for two days in a row
. Treatment may need to be repeated in one week. Children—Dose is based on body weight and must be determined by your doctor.
What are the side effects of piperazine?
- Blurring of vision.
- clumsiness.
- crawling or tingling feeling of the skin.
- irregular, twisting movement, especially of the face, arms, and legs.
- joint pain.
- skin rash or itching.
What is the use of piperazine?
Piperazine is used to treat:
common roundworms (ascariasis)
and. pinworms (enterobiasis; oxyuriasis).
What does piperazine citrate do?
Piperazine citrate is used as a second-line treatment for
treating roundworm infections
caused by Ascaris lumbricoides and pinworm infections caused by Enterobius vermicularis (oxyuris). It paralyses the worm which is then expelled by the digestive tract.
Is piperazine an antibiotic?
Piperazine, also called hexahydropyrazine,
anthelmintic drug
used in the treatment of intestinal roundworm infection in humans and domestic animals (including poultry) and against pinworm infection in humans. It is administered orally, in repeated doses, usually as the citrate salt.
What is the brand name of piperazine?
Piperazine Citrate (
GSK
) (750mg/ 5mL)
Manufacturer: Glaxo SmithKline Pharmaceuticals Ltd.
Is piperazine an antihistamine?
A selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria. An
antihistamine and antiemetic drug
for the treatment of allergy symptoms and prevention of nausea and vomiting.
How long does piperazine stay in urine?
The major component in both urine and faeces was unchanged piperazine (in urine respectively 82% and 61% at
24 hours and 168 hours after administration
), although some unidentified metabolites were present in both excreta.
Is piperazine a drug?
Piperazine is a
medication used to treat roundworm and pinworm
. Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953.
What does piperazine feel like?
The stimulant effects of piperazines are similar to MDMA (ecstasy) but dose for dose they are not as potent. Effects can last for 6 to 8 hours and include feelings of:
euphoria
.
being alert, alive and full of energy
.
How is piperazine made?
Although many piperazine derivatives occur naturally, piperazine itself can be synthesized by
reacting alcoholic ammonia with 1,2-dichloroethane
, by the action of sodium and ethylene glycol on ethylene diamine hydrochloride, or by reduction of pyrazine with sodium in ethanol.
Is example of piperazine derivatives?
The piperazine derivatives include 1-benzylpiperazine (BZP), 1,3-trifluoromethylphenylpiperazine (TFMPP),
1-(3-chlorophenyl) piperazine (mCPP)
and 1-(4-methoxyphenyl) piperazine (MeOPP); a full summary of their chemical properties is presented in the ‘Physical Descriptions’ section.
What deworming medicine is best for cats?
The best broad-spectrum dewormer
We recommend
Bayer Drontal Broad Spectrum Dewormer
because it is safe, effective, and eliminates all parasites within seven days. No other cat dewormer kills as many different types of worms as Drontal.
What is piperazine ring?
Piperazine (1,4-hexahydropyrazine) is
a cyclic organic molecule possessing two nitrogen atoms in opposite positions within
a 6-member heterocyclic ring.
