DECIDUALIZATION AND DECIDUAL STRUCTURE
Decidualization is the
differentiation of elongated, fibroblast‐like mesenchymal cells in the uterine stroma to rounded, epithelioid‐like cells during the menstrual cycle and pregnancy
.
What is Decidualized endometrial tissue?
Decidualization refers to
the functional and morphological changes that occur within the endometrium to form the decidual lining into which the blastocyst implants
. These changes include the recruitment of leukocytes and, importantly, the differentiation of endometrial stromal fibroblast cells (ESCs) into DSCs.
What does Decidualized mean?
Decidualization refers to
the functional and morphological changes that occur within the endometrium to form the decidual lining into which the blastocyst implants
. These changes include the recruitment of leukocytes and, importantly, the differentiation of endometrial stromal fibroblast cells (ESCs) into DSCs.
What is the dictionary meaning of decidua?
1 :
the part of the endometrium that in higher placental mammals undergoes special modifications in preparation for and during pregnancy and is cast off at parturition
. 2 : the part of the endometrium cast off in the process of menstruation.
Is decidua an endometrium?
The decidua is
the modified mucosal lining of the uterus
(that is, modified endometrium) that forms in preparation for pregnancy. It is formed in a process called decidualization under the influence of progesterone. Endometrial cells become highly characteristic.
Is Decidual reaction normal?
The decidual reaction is most prominent
between 18 and 32 weeks with a decline near term
. There is also a wide variation in the extent of decidual reaction during normal pregnancy preventing its use as a sensitive indicator of normal versus abnormal pregnancy.
Does gestational sac confirm pregnancy?
The gestational sac is
usually the first sign of pregnancy on ultrasound
. When correlated with HCG levels, the presence of a gestational sac can be very helpful in detecting ectopic or heterotopic pregnancy. It can also be used to determine if you have experienced a very early miscarriage.
Where are stromal cells located?
It is well known that stromal cells arise and are stored in
the bone marrow
until maturation and differentiation. They are located in the stroma and aid hematopoietic cells in forming the elements of the blood.
What is uterine stroma?
Abstract. Endometrial stromal sarcoma (ESS) is
a rare malignant tumor of the endometrium
, occurring in the age group of 40–50 years. This is a case of low-grade ESS presenting as rapid enlargement of a fibroid uterus. Because of her secondary infertility, she was planned for myomectomy.
What happens during Decidualization?
During pregnancy
The decidual reaction is seen in very early pregnancy in the generalized area where the blastocyst contacts the endometrial decidua. It consists of an
increase in secretory functions of the endometrium at the area of implantation
, as well as a surrounding stroma that becomes edematous.
What does Grandular mean?
1a : of,
relating to, or involving glands, gland cells, or their products
. b : having the characteristics or function of a gland.
What is the meaning of Desigual?
Desigual (Spanish: [desiˈɣwal], Catalan: [dəziˈɣwal]; meaning
“unequal, uneven”
) is a Spanish fashion company. It is headquartered in Barcelona, Catalonia, Spain.
What are the three layers of the decidua?
- the superficial compact layer,
- the intermediate spongy layer,
- the thin basal layer.
Does Decidual reaction mean pregnancy?
A decidual reaction is
a feature seen in very early pregnancy where there is thickening of the endometrium around the gestational sac
. A thin decidual reaction of less than 2 mm is considered one of the features suggestive of an anembryonic pregnancy
2
.
Is decidua part of the placenta?
Placental Membrane
The fetal part of the placenta is known as the chorion.
The maternal component of the placenta
is known as the decidua basalis. Oxygen and nutrients in the maternal blood in the intervillous spaces diffuse through the walls of the villi and enter the fetal capillaries.
How is decidua formed?
It is formed
during the secretory phase of the menstrual cycle as a result of elevated ovarian hormones such as estrogen and progesterone
. The decidua is composed of glands, immune cells, blood and lymph vessels, and decidual stromal cells (DSCs) and fetal extravillous trophoblast (Mori et al., 2016).
