Thyroid-stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called
thyrotrophs
What part of pituitary secretes TSH?
Thyroid-Stimulating Hormone
TSH is released from
the anterior pituitary
in response to thyrotropin-releasing hormone (TRH) from the hypothalamus. As discussed shortly, it triggers the secretion of thyroid hormones by the thyroid gland.
What cell produces TSH?
TSH Synthesis and Secretion. TSH is synthesized in
the thyrotropic cells of the anterior pituitary
. These cells represent approximately 5% of the endocrine cells of the pituitary gland and localize in the anterior median part of the gland.
What part of the brain secretes TSH?
The hypothalamus
is part of the brain and produces TSH Releasing Hormone (TRH) which tells the pituitary gland to stimulate the thyroid gland (release TSH).
What is the thyroid hormone secreted from anterior pituitary gland?
TSH
is a peptide hormone produced by the anterior pituitary.
What is another name for the anterior pituitary?
The anterior pituitary, also known as
adenohypophysis
, is a classic endocrine gland in that it is composed of secretory cells of epithelial origin supported by connective tissue rich in blood and lymphatic capillaries.
What are the 6 anterior pituitary hormones?
The anterior pituitary gland produces six major hormones:
(1) prolactin (PRL), (2) growth hormone (GH)
, (3) adrenocorticotropic hormone (ACTH), (4) luteinizing hormone (LH), (5) follicle-stimulating hormone (FSH), and (6) thyroid-stimulating hormone (TSH) (Table 401e-1).
What's a good TSH level?
TSH normal values are
0.5 to 5.0 mIU/L
. Pregnancy, a history of thyroid cancer, history of pituitary gland disease, and older age are some situations when TSH is optimally maintained in different range as guided by an endocrinologist. FT4 normal values are 0.7 to 1.9ng/dL.
What causes the TSH levels to rise?
Your TSH levels will be increased, if:
Your thyroid gland is not working as it normally should
.
Your thyroid gland is infected or inflamed
, as in Hashimoto's thyroiditis, or autoimmune thyroiditis. This occurs when your body is attacking your thyroid gland, for some unknown reason.
What organs does the thyroid affect?
The thyroid gland produces hormones that regulate the body's metabolic rate controlling
heart, muscle and digestive function
, brain development and bone maintenance.
What is normal TSH level for female?
The normal range of TSH levels in non-pregnant adult women is
0.5 to 5.0 mIU/L
. In women, during the menstruation cycle, pregnancy, or after menopause, TSH levels may fall slightly outside the normal range, because of fluctuating levels of estrogen.
What does TSH lab test show?
Thyroid-stimulating hormone (TSH)
signals the thyroid gland to make hormones
that control how your body uses and stores energy, called your metabolism. Testing the level of TSH in your blood can reveal if your thyroid gland is functioning normally.
What are thyroid levels called?
The test, called a thyroid function test, looks at levels of thyroid-stimulating hormone (
TSH
) and thyroxine (T4) in the blood. Doctors may refer to this as “free” T4 (FT4). A high level of TSH and a low level of T4 in the blood could mean you have an underactive thyroid.
What are the functions of the anterior pituitary gland?
The anterior pituitary gland produces the following hormones and releases them into the bloodstream: adrenocorticotropic hormone, which stimulates the adrenal glands to secrete steroid hormones, principally cortisol. growth hormone, which regulates growth,
metabolism and body composition
.
What controls hormone released from the anterior pituitary gland?
The clusters of cells that produce the six anterior pituitary hormones are under
hypothalamic control
. Unlike the posterior pituitary which basically stores hormones produced by the hypothalamus, the hypothalamus regulates the anterior pituitary via secreting “releasing hormones,” somatostatin and dopamine.
What are the disorders of the pituitary gland?
- Acromegaly.
- Craniopharyngioma.
- Cushing Disease / Cushing Syndrome.
- Growth Hormone Deficiency.
- Nonfunctioning Pituitary Adenoma.
- Prolactinoma.
- Rathke's Cleft Cyst.
