Side effects of Amlodipine are quite rare in veterinary medicine, but
in some cases, the cat or dog can show lethargy
, loss of appetite, weight loss, swelling of the gums or a slight increase in heart rate.
What are the side effects of amlodipine in dogs?
Side effects in dogs may include
gingival (gum) overgrowth
. Serious side effects include a very low or very fast heart rate, collapse, severe weakness, changes in urination, limb swelling, or abnormal bleeding.
What are the most common side effects of amlodipine?
- swelling of the hands, feet, ankles, or lower legs.
- headache.
- upset stomach.
- nausea.
- stomach pain.
- dizziness or lightheadedness.
- drowsiness.
- excessive tiredness.
How long until amlodipine side effects go away?
Amlodipine’s half-life is
30 to 50 hours
. In other words, it takes about 30 to 50 hours for your body to get rid of half of a dose of amlodipine. It usually takes about five half-lives for a drug to leave your system entirely.
Can blood pressure medicine cause extreme fatigue?
Blood pressure medications.
Beta-blockers, like atenolol (Tenormin), metoprolol tartrate (Lopressor), metoprolol succinate (Toprol XL), and propranolol hydrochloride (Inderal), to name a few. They work by slowing down your heart, which
can make you tired
.
Can amlodipine cause sleeplessness?
Results: It was found that
patients receiving amlodipine in the combination antihypertensive therapy had insomnia manifestations much less frequently as compared to indapamide
. A statically significant decrease in blood pressure (BP) and a higher proportion of patients with target BP were observed in both groups.
How much amlodipine Can a dog have?
Amlodipine besylate is available as 2.5mg and 5 mg tablets. The usual dose to treat systemic hypertension in cats is 0.625mg (1/4 of a 2.5mg tablet) by mouth once a day. The usual dose for dogs is
0.025 to 0.05 mg/lb by mouth once a day
.
How much amlodipine can a dog take?
Amlodipine besylate for dogs is usually available in 2.5 mg, 5 mg, or 10 mg tablets. It can also be given as an oral solution, soft chews, or a transdermal gel. A general dosing guideline is as follows:
0.1 mg – 0.4 mg per kilogram of weight, once to twice daily
.
Can a dog overdose on amlodipine?
Overdose.
Overdose with amlodipine will cause very low blood pressure and slow the heart rate
. If you suspect your pet or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A.’s Animal Poison Control Center at 888.426. 4435.
Why is amlodipine being recalled?
Authorities found a carcinogen (cancer-causing substance) called NDEA in the combination pills
, and these pills are now on the FDA’s recall list along with other Valsartan drugs.
Why is amlodipine given at night?
New research suggests that taking your blood pressure medication at bedtime
may more effectively reduce your risk of illness or death due to heart and blood vessel disease
. Timing of medication is important because blood pressure follows a daily rhythm. It rises higher during the day and falls at night when we sleep.
Does amlodipine have a calming effect?
How it works. Amlodipine may be used to treat heart conditions such as angina and high blood pressure.
Amlodipine inhibits the influx of calcium ions across cardiac (heart) and smooth muscle causing relaxation of these muscles and dilation (widening)
.
Can amlodipine be stopped abruptly?
If you have been using this medicine regularly for several weeks,
do not suddenly stop using it
. Stopping suddenly may cause your chest pain or high blood pressure to come back or get worse. Check with your doctor for the best way to reduce gradually the amount you are taking before stopping completely.
What is the peak time for amlodipine?
After oral administration of therapeutic doses, amlodipine is well absorbed with peak blood levels between
6-12 hours post dose
. Absolute bioavailability has been estimated to be between 64 and 80%.
What foods should I avoid when taking amlodipine?
Amlodipine Interactions with Food and Herbs
Grapefruit Juice
: Grapefruit juice may increase the level of amlodipine in the blood stream. Pleurisy Root: Pleurisy roots are not recommended with most cardiovascular medications due to the cardiac glycoside content of the root.
How do you stop fatigue from blood pressure medication?
A program of nutrition and exercise can increase blood flow and get you feeling more energetic as your body adjusts to blood pressure medication
. Aerobic exercise, such as walking, is considered safe for most people.
How do you stop tiredness from medication?
She also suggests that you keep healthy sleep habits to get a good night’s rest; limit over-the-counter drugs that have drowsiness as a side effect; limit other substances that can cause tiredness, such as alcohol; and talk to your pharmacist to see if it’s possible to take the medication at night, when you’re already …
What is lethargy a symptom of?
Lethargy is a symptom of
many acute (abrupt onset) conditions, including the flu, stomach viruses, fever, dehydration, and nutritional deficiencies
. Other serious medical conditions that cause lethargy may include, but are not limited to: Carbon monoxide poisoning. Hyperthyroidism (excess production of thyroid hormone)
Should amlodipine be taken in the morning or at night?
It does not matter what time of day you take amlodipine (morning or evening) but
it is best to take it at the same time every day
, when you are most likely to remember, for more even blood levels and therefore effectiveness. Amlodipine is a calcium channel blocker that dilates blood vessels and improves blood flow.
Is amlodipine hard on the kidneys?
Amlodipine and lisinopril
should not cause kidney damage
and in fact are used to treat high blood pressure and slow the progression of chronic kidney disease (CKD).
Does amlodipine cause depression?
Mood changes such as depression or anxiety
. Difficulty sleeping (insomnia). Tremor. Vomiting.
What are the Side-Effects of levetiracetam in dogs?
The most common side effects include
sleepiness and incoordination
in dogs. In cats, a decreased appetite, incoordination, drooling, and sleepiness most commonly occur. Serious side effects include persistent vomiting or sudden changes in behavior.
What is Norvasc 5mg used for in dogs?
The main use of amlodipine is
to treat high blood pressure
in cats and dogs. It is also used as a vasodilator drug in the treatment of congestive heart failure in dogs.
What does spironolactone do for dogs?
Spironolactone is a diuretic that is used in dogs and cats
to treat congestive heart failure and other conditions where the body retains excess fluid
.
Is Norvasc toxic to dogs?
Norvasc or other drugs that contain amlodipine bensylate
can cause several side effects in dogs
. If the dosage is too high or if a dog is overexposed, then the dog may develop the opposite of high blood pressure, which is hypotension, or low blood pressure. This can lead to weakness, depression, or fainting.
Does amlodipine cause loss of appetite?
Use extra care during exercise or hot weather. Check with your doctor right away if you or your child have pain or tenderness in the upper stomach, pale stools, dark urine,
loss of appetite
, nausea, vomiting, or yellow eyes or skin.
How much amlodipine is lethal?
The peak plasma amlodipine concentration was found to be 0.185 mg/L approximately 11 h after ingestion. Death occurred 26 h after ingestion. An overdose of
140 mg
amlodipine by a 15-year-old girl resulted in death 6 h after ingestion despite resuscitation mea- sures and treatment with calcium, adrenaline, and atropine.
