Can Benadryl Cause Kidney Failure In Dogs?

by | Last updated on January 24, 2024

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While these side effects can be troublesome, they often aren't serious. However, there are some that are worth keeping an eye on, such as urinary retention. This

can cause trouble for dogs that may have existing liver or kidney problems prior to using the medication, as it can cause the issue to worsen

.

Can Benadryl cause problems in dogs?


Some dogs develop an allergic reaction to Benadryl

. If your dog starts having symptoms of an allergic reaction, seek veterinary care immediately.

Is Benadryl OK for kidney disease?

Diphenhydramine is a commonly used drug for allergic reactions, pruritus, insomnia, various off-label uses, and it may have dependence properties.

Clinicians should use caution when using it in patients with kidney disease and dialysis due to the highly protein-bound characteristics and potential for causing toxicity

.

What happens if I give my dog too much Benadryl?

Overdose. An overdose can be fatal. If your dog eats too much Benadryl, call the emergency vet or poison control hotline at (888) 426-4435 right away. Symptoms of overdose include

dilated pupils, constipation, rapid heartbeat, behavioral changes, and seizures

.

Does Benadryl cause liver or kidney damage?

Despite widespread use over many decades,

diphenhydramine has not been linked to liver test abnormalities or to clinically apparent liver injury

. The reason for its safety may relate its short half-life and limited duration of use.

Can Benadryl cause urinary retention?


Urinary retention can also be caused by

. Drugs like antihistamines (Benadryl®), antispasmodics (like Detrol®), opiates (like Vicodin®) and tricyclic antidepressants (like Elavil®) can change the way the bladder muscle works.

Can I give my dog Benadryl every day?

According to the Merck Veterinary Manual, the safe dosage is 2-4 milligrams of medication per kilogram of weight, or 0.9 to 1.8 milligrams per pound. This amount can be administered

two to three times daily

, depending on your dog's symptoms.

What Benadryl is safe for dogs?

Most diphenhydramine (Benadryl) tablets are 25 mg, which would be the appropriate size for a 25-pound dog. Smaller dogs will require you to cut or divide these 25-mg pills. In this case,

children's Benadryl in the chewable tablets

may be a good option. These come in dosages of 12.5 mg.

How much Benadryl can I give my 80lb dog?

How many mg of Benadryl do I give to the dog? A standard dose of Benadryl for dogs is

one mg per one pound

, or 2.2 mg per one kilogram. If you prefer to use pounds, multiply the dog's weight by 1 mg: dog's weight in lb × 1 mg.

Which medications can cause kidney damage?

  • Antibiotics.
  • Diuretics.
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
  • Proton Pump Inhibitors (PPIs)
  • Supplements.
  • Laxatives.
  • If You Have Kidney Disease, Other Medications Can Be Harmful.

What is the side effect of Benadryl?


Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat

may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What medications should be avoided with kidney disease?

  • Cholesterol medications. The dosing of certain cholesterol medications, known as “statins”, may need to be adjusted if you have chronic kidney disease.
  • Pain medications. …
  • Anti-microbial meds. …
  • Diabetes medications. …
  • Upset stomach/antacid medications.

How much Benadryl is toxic to a dog?

The lethal dose (LD

50

) for diphenhydramine in dogs ranges between

24 to 30 mg/kg BW

by IV administration, and death has been attributed to neuromotor excitement and convulsions, followed by respiratory failure and myocardial depression (16).

How long does it take for Benadryl to get out of a dog's system?

It usually takes

24 hours

for Benadryl to wear off and stop working. However, for dogs with liver or kidney disease, the effects can last longer. Always talk to your veterinarian before giving Benadryl, especially if your dog has chronic liver, kidney, or heart problems.

Does Benadryl affect a dog's liver?

Diphenhydramine can alter the results of skin allergy testing; discontinue this medication at least 2 weeks before testing. This short-acting medication should stop working within 24 hours, although

effects can be longer in pets with liver or kidney disease

.

What are the side effects of long term use of antihistamines?

These common side effects include

sedation, impaired motor function, dizziness, dry mouth and throat, blurred vision, urinary retention and constipation

. Antihistamines can worsen urinary retention and narrow angle glaucoma. The antihistamines rarely cause liver injury.

Are there any side effects to taking Benadryl every night?

Benadryl and some other antihistamine drugs can sometimes cause

decreased memory, confusion, and trouble thinking

. These side effects are more common in seniors. In addition, taking Benadryl long term might increase the risk of dementia such as Alzheimer's disease, especially in seniors.

Can long-term use of Benadryl be harmful?

Exposure to diphenhydramine over the short term can make older folks a little squirrely, but

long-term use over many years may lead to Alzheimer's disease

. If people are unable to achieve a good night's sleep, they really need to consult with a physician.

Do antihistamines cause bladder problems?

Trouble is,

certain antihistamines can relax the bladder, blunting its ability to push out urine

. In the end, there is still some urine left in your bladder, which means it will fill up again faster and send that “gotta pee” signal to your brain sooner.

Does Benadryl affect urination?

Because of Benadryl's dehydrating effects, it may cause dry mouth, constipation, blurred vision, and

urinary retention

, which can increase the risk of developing urinary tract infections (UTIs) or affect kidney function.

How often can you give your dog Benadryl?

You can give Benadryl to your dog

every eight to twelve hours

, so about two to three times per day. If you use the product frequently, it may begin to lose effectiveness over time. In most cases, it's better to administer medication before exposure to allergens.

How much Benadryl can you give a 10lb dog?

Very Small Dogs (4-10 pounds):

1/4 tablet
Larger dogs: 1 tablet per 25 pounds body weight

How do I euthanize my dog at home with Tylenol PM?


It is not recommended to use, or consider using Tylenol PM to euthanize a dog at home

. You must contact or reach out to your vet for the correct euthanasia practices. The studies are completed while using IV dosages, typically, the oral dosage could be even higher than IV.

Rebecca Patel
Author
Rebecca Patel
Rebecca is a beauty and style expert with over 10 years of experience in the industry. She is a licensed esthetician and has worked with top brands in the beauty industry. Rebecca is passionate about helping people feel confident and beautiful in their own skin, and she uses her expertise to create informative and helpful content that educates readers on the latest trends and techniques in the beauty world.