This change in a copy of the gene making factor VIII or factor IX is called a hemophilia allele. Most people who have hemophilia are born with it.
It almost always is inherited (passed down) from a parent to a child
.
Can haemophilia be inherited?
Most people who have hemophilia are born with it.
It almost always is inherited (passed down) from a parent to a child
.
Can males carry the hemophilia gene?
Thus, males can have a disease like hemophilia if
they inherit an affected X chromosome that has a mutation in either the factor VIII or factor IX gene
. Females can also have hemophilia, but this is much rarer. In such cases both X chromosomes are affected or one is affected and the other is missing or inactive.
Can hemophiliacs have babies?
If the mother is a hemophilia carrier,
there is a chance that the baby will be born with hemophilia
. In families with a known history of hemophilia, or in those with a prenatal genetic diagnosis of hemophilia, one can plan special testing for hemophilia before the baby’s delivery.
Can two normal parents produce a hemophiliac son?
If the baby gets the Y chromosome from the father it will be a boy. The son can get from the
mother either her X chromosome with the hemophilia gene
or her X chromosome with the normal blood clotting gene. If the son gets his mother’s X chromosome with the hemophilia gene he will have hemophilia.
Why is hemophilia more common in males?
Since males have only a single copy of any gene located on the X chromosome, they cannot offset damage to that gene with an additional copy as can females. Consequently,
X-linked disorders such
as Hemophilia A are far more common in males.
Does the royal family still carry hemophilia?
The last known descendant to suffer from the disease was Infante Don Gonzalo (1914-1934), who died in a car crash at nineteen.
Today, no living members of reigning dynasties are known to have symptoms of hemophilia
.
Do female hemophiliacs menstruate?
Women and girls routinely put
up with heavy menstrual bleeding
, often accompanied by other tell-tale symptoms, such as bruising and prolonged bleeding after dental work or childbirth, without realising that they could have a genetic bleeding disorder.
Why females are not affected by haemophilia?
“Growing up, we understood that men had hemophilia and women were “carriers.” Women passed along the X-linked gene, but did not actually get hemophilia
because (it was believed) that the “good X chromosome” compensated for the X chromosome that carried hemophilia
.
Can hemophilia be cured?
There is currently no cure for hemophilia
. Effective treatments do exist, but they are expensive and involve lifelong injections several times per week to prevent bleeding.
Can you live a normal life with hemophilia?
Haemophilia patients can’t live a normal life
, and have short life expectancy. Fact: With several medical advancements, people haemophilia lead a near normal life expectancy.
What are the 3 types of hemophilia?
- Hemophilia A: Caused by a lack of the blood clotting factor VIII; approximately 85% of hemophiliacs have type A disease.
- Hemophilia B: Caused by a deficiency of factor IX.
- Hemophilia C: Some doctors use this term to refer to a lack of clotting factor XI.
What foods to avoid if you have hemophilia?
- large glasses of juice.
- soft drinks, energy drinks, and sweetened tea.
- heavy gravies and sauces.
- butter, shortening, or lard.
- full-fat dairy products.
- candy.
- foods containing trans fats, including fried. foods and baked goods (pastries, pizza, pie, cookies, and crackers)
What race is most affected by hemophilia?
The average age of persons with hemophilia in the United States is 23.5 years. Compared to the distribution of race and ethnicity in the U.S. population,
white race is more common
, Hispanic ethnicity is equally common, while black race and Asian ancestry are less common among persons with hemophilia.
How can you tell if someone has hemophilia?
- Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work.
- Many large or deep bruises.
- Unusual bleeding after vaccinations.
- Pain, swelling or tightness in your joints.
- Blood in your urine or stool.
- Nosebleeds without a known cause.
- In infants, unexplained irritability.
