Can I Eat Grapefruit When Taking Ibuprofen?

by | Last updated on January 24, 2024

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Can I eat grapefruit when taking ibuprofen? Grapefruit interferes with proteins in the small intestine and liver that normally break down many medications.

Eating grapefruit or drinking grapefruit juice while taking these medications can lead to higher levels of them in your blood

— and more side effects.

What medications should not be eaten with grapefruit?


Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin)

. Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine). Some organ-transplant rejection drugs, such as Neoral and Sandimmune capsule or oral solution (both cyclosporine).

Does grapefruit interact with Nsaids?

Sometimes one medicine may keep another medicine from working well. Or you may get a side effect you didn’t expect.

Medicines may also interact with certain foods or drinks, like grapefruit juice and alcohol

.

Does grapefruit interfere with pain medication?


Yes. Grapefruit and certain other citrus fruits, such as Seville oranges, can interfere with several kinds of prescription medications

.

What meds does grapefruit react with?

Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).

Does grapefruit affect blood pressure?

Studies have shown that

eating grapefruit every day can lower systolic blood pressure by as much as five points

. This may be due to grapefruit’s high levels of potassium, which neutralize the negative effects of sodium (a common cause of hypertension).

Is grapefruit good for high blood pressure?

Citrus fruits, including grapefruit, oranges, and lemons,

may have powerful blood-pressure-lowering effects

. They’re loaded with vitamins, minerals, and plant compounds that may help keep your heart healthy by reducing heart disease risk factors like high blood pressure ( 4 ).

Can I eat grapefruit after taking Tylenol?

Grapefruit juice increases bioavailability of a number of drugs because of inhibition of the P-glycoprotein pump and inhibition of intestinal cytochrome P450 3A4 enzyme. However,

interaction between acetaminophen (also known as paracetamol in many parts of the world) and grapefruit juice has never been reported

.

Can grapefruit be toxic?


One whole grapefruit, or a small glass (200 mL, 6.8 US fl oz) of grapefruit juice, can cause drug overdose toxicity

.

Why should you not eat grapefruit when taking oxycodone?


Grapefruit juice inhibited the CYP3A4-mediated first-pass metabolism of oxycodone, decreased the formation of noroxycodone and noroxymorphone and increased that of oxymorphone

. We conclude that dietary consumption of grapefruit products may increase the concentrations and effects of oxycodone in clinical use.

Does grapefruit get you higher?


No, there’s no reason at all it would work

. Cannabinoids are not metabolised by the CYP450 isozymes that grapefruit juice inhibits (CYP3A4, 1A2 maybe).

Does grapefruit juice make medicine stronger?


Compounds in grapefruit called furanocoumarin chemicals are the cause of the increased medication potency

. These chemicals interact with the cytochrome P450 3A4 (CYP3A4) enzyme, found in the small intestine and liver, which partially inactivates many medications under normal circumstances.

How long does grapefruit juice stay in your system?

The interaction potential of even high amounts of grapefruit juice with CYP3A4 substrates dissipates within

3 to 7 days

after ingestion of the last dose of grapefruit juice.

What fruits interact with drugs?

Which fruit and fruit products can cause these interactions? Fruits associated with medicine interactions include

orange, pomelo, pomegranate, cranberry, grape, apple, and grapefruit

.

Why is grapefruit good for you?

Like many citrus fruits, grapefruit is

loaded with vitamin C, a nutrient shown to help boost your body’s immune system

. Grapefruit is also loaded with Vitamin A, another vitamin that has been proven to help immune function. This powerful combination could help keep the amount of time you spend sick to a minimum.

Is it OK to eat grapefruit everyday?


Regularly consuming grapefruit is thought to improve heart health by reducing risk factors for heart disease, such as high blood pressure and cholesterol

. In one study, people who ate grapefruit 3 times daily for 6 weeks experienced significant reductions in blood pressure over the course of the study.

Is grapefruit a blood thinner?

Grapefruit. Similar to leafy greens,

grapefruit and grapefruit juice contain compounds that can offset the work of blood thinners

. Eating grapefruit or drinking the juice can also lead to bleeding.

Does grapefruit burn belly fat?

While

no clinical data confirm that eating grapefruit will literally burn off your belly fat

to the point that you will be blessed with a svelte physique within days, some studies show that eating this fruit may naturally support your weight loss goals, and in turn, help reduce your abdominal fat.

What food lowers blood pressure quickly?

  • Skim or 1% milk, yogurt, Greek yogurt (calcium-rich foods can lower blood pressure).
  • Lean meat.
  • Skinless turkey and chicken.
  • Low-salt, ready-to-eat cereals.
  • Cooked hot cereal (not instant).
  • Low-fat and low-salt cheeses.
  • Fruits (fresh, frozen, or canned without added salt).

Is grapefruit good for arteries?

Pink and red grapefruit are

good sources of beta carotene (a source of vitamin A) and lycopene, an antioxidant “cousin” to beta carotene that has been linked to lower stroke risk

.

When should you not eat grapefruit?

  • Atorvastatin (Lipitor)
  • Lovastatin (Mevacor)
  • Simvastatin (Zocor)

How fast does grapefruit lower blood pressure?

“In the present study, a single intake of grapefruit juice increased the plasma concentration of nifedipine and also decreased blood pressures

3 hours

after intake of grapefruit juice…”

Why can’t diabetics have grapefruit?

Grapefruit is unique in that

it has an enzyme-binding ability

. This means that it may cause certain medications to pass from the GI tract into the bloodstream faster than normal, raising the amount of medication in your bloodstream, which can be potentially dangerous.

Does grapefruit get you drunk faster?

This meant that the taste of alcohol had to be masked, and after some experimentation Dr. Bailey concluded that grapefruit juice was up to the task. To the researchers’ surprise,

the alcohol had no effect

, but in both groups the blood levels of felodipine were three times higher than expected.

What happens if I drink grapefruit juice everyday?

Finally, grapefruit contains various antioxidant plant compounds. These have many health benefits, including reducing the risk of developing many diseases. Drinking grapefruit juice every day may

boost your immune system, keep you hydrated, and reduce your risk of developing some diseases

.

What fruits interfere with high blood pressure medication?

People taking ACE inhibitors or ARBs should limit their intake of high-potassium foods like

bananas, oranges, avocados, tomatoes, white and sweet potatoes and dried fruits —, especially apricots

.

Why can’t diabetics have grapefruit?

Grapefruit is unique in that

it has an enzyme-binding ability

. This means that it may cause certain medications to pass from the GI tract into the bloodstream faster than normal, raising the amount of medication in your bloodstream, which can be potentially dangerous.

What should you not take with blood pressure medicine?

  • Decongestants, such as those that contain pseudoephedrine.
  • Pain medicines (NSAIDs), such as ibuprofen and naproxen.
  • Cold and influenza medicines. These often contain decongestants and NSAIDs.
  • Some antacids and other stomach medicines. …
  • Some natural health products.
Sophia Kim
Author
Sophia Kim
Sophia Kim is a food writer with a passion for cooking and entertaining. She has worked in various restaurants and catering companies, and has written for several food publications. Sophia's expertise in cooking and entertaining will help you create memorable meals and events.