Can Sertraline Induce Menstrual Cycle?

by | Last updated on January 24, 2024

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An antidepressant, such as Prozac (fluoxetine) or Zoloft (sertraline), can be an effective way to relieve symptoms of depression—but it’s not right for everyone. In addition to possible side effects,

some antidepressants can even cause your period to be late or delayed

.

Does paroxetine affect menstrual cycle?

Open-trial studies of paroxetine found it to be effective in the acute phase for the treatment of PMDD [27], and found

symptom reduction to persist across ten consecutive menstrual cycles

[28].

Can sertraline mess with hormones?


In adult males, the use of SSRIs has been associated with hormonal abnormalities

and decreased fertility such as low levels of testosterone (TS), luteinizing hormone (LH), and follicle stimulating hormone (FSH), and elevated level of prolactin (Safarinejad, 2008).

Does sertraline affect fertility?

Sertraline and fertility


For men, sertraline may reduce sperm quality, but it’s not known whether this reduces fertility or not

. Speak to your doctor if you’re having difficulty trying for a baby. For women, there’s no evidence to suggest that taking sertraline reduces your fertility.

Does sertraline increase estrogen?

Sertraline shared the same properties with fluoxetine, but also

increased the estradiol-mediated transcriptional activity

. Paroxetine presented only one type of effect, the ability to increase the estradiol-mediated transcriptional activity.

Does sertraline increase estrogen levels?


found that fluoxetine, paroxetine, citalopram, escitalopram, sertraline and fluvoxamine all increase the estrogen/ androgen ratio

, which is an indicator of aromatase activity [66] .

Does serotonin increase estrogen?

Our review of data from a variety of fields suggests that

serotonin is one way that estrogen is exerting its effects on physiology and pathology in women

. The primary function of E2 is reproductive, and serotonergic mediation of the estrogen system likely provides reproductive benefits that are not yet understood.

Why might your period be late?

Your cycle

Missed or late periods happen for many reasons other than pregnancy. Common causes can range from

hormonal imbalances to serious medical conditions

. There are also two times in a woman’s life when it’s totally normal for her period to be irregular: when it first begins, and when menopause starts.

What should I do for late periods?

  1. A healthy lifestyle, with regular physical exercise and a healthy and varied diet, rich in fruits and vegetables;
  2. Taking the contraceptive pill, as it can help to regulate the menstrual cycle;

Can anxiety delay menstruation?

Stress causes your body to go into fight or flight mode—it’s just the way we’re wired. When you’re in this mode, it affects your hormones, which in turn affect your ovulation and, of course, your period. This means

you may have periods that are late or even stop completely for several months

.

Can sertraline cause infertility in females?


No, there isn’t any data to suggest that anti-depressants affect female fertility

(so far); however, one study did find that it had an effect on male fertility. According to the research, sperm exposed to anti-depressants has increased DNA fragmentation compared to sperm that has never been exposed to anti-depressants.

Can antidepressants affect ovulation?

Women taking serotonin uptake inhibitors (SSRIs) to help them cope with infertility are actually increasing their serum prolactin to an unhealthy level. This hyperprolactinemia, in turn,

blocks ovulation

.

How can I boost my fertility?

  1. Eat foods rich in antioxidants. Antioxidants like folate and zinc may improve fertility for both men and women. …
  2. Eat a bigger breakfast. …
  3. Avoid trans fats. …
  4. Cut down on carbs if you have PCOS. …
  5. Eat fewer refined carbs. …
  6. Eat more fiber. …
  7. Swap protein sources. …
  8. Choose high fat dairy.

Can Escitaloprám affect your period?

Antidepressants as a group

do not seem to have any universal effect on women’s menstrual cycles

, but in some women there may be changes either in the cycle itself, or in the menstrual period.

Can sertraline cause gyno?

In other cases, a medication may have some risk of causing gynecomastia, but it’s not very common. For example, sertraline is a common antidepressant used to treat several mental health conditions.

It’s linked to gynecomastia, but it’s thought to happen to less than 1% of people who take it

.

What are the symptoms of low estrogen?

  • Dry skin.
  • Tender breasts.
  • Weak or brittle bones.
  • Trouble concentrating.
  • Moodiness and irritability.
  • Vaginal dryness or atrophy.
  • Hot flashes and night sweats.
  • Irregular periods or no periods (amenorrhea).

Do antidepressants cause hormonal imbalances?

What the Research Shows: Can Antidepressants Cause Hormone Imbalance?

SSRIs, SNRIs, and TCAs increase levels of hormones, especially serotonin

. While serotonin is a good thing in moderation, too much of any hormone can cause issues.

Do antidepressants affect fertility?

found that

women who took antidepressants for more than six months had 2.9 times the odds of infertility

(95% CI 0.9-8.3). This finding was based on five cases who took antidepressants.

Is sertraline a hormone?

Zoloft (sertraline chloride) is a selective serotonin reuptake inhibitor (SSRI) used to treat a variety of psychiatric disorders, including depression, PTSD, OCD, social anxiety disorder and panic attacks.

Zoloft works by balancing the levels of serotonin, a hormone

that controls mood, in the brain.

Do SSRIs mess with hormones?


Acute administration of SSRIs increases the secretion of several hormones, but chronic treatment with SSRIs does not alter basal blood levels of hormones

. However, adaptive changes are induced by long-term treatment with SSRIs in serotonergic, noradrenergic and peptidergic neural function.

Does serotonin affect your hormones?

Mood: Serotonin is in the brain. It is thought to regulate mood, happiness, and anxiety. Low levels of serotonin are linked to depression, while

increased levels of the hormone may decrease arousal

.

What happens if I get too much serotonin?

Serotonin is a chemical that the body produces naturally. It’s needed for the nerve cells and brain to function. But too much serotonin

causes signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures)

. Severe serotonin syndrome can cause death if not treated.

How late should my period be before I worry?

Your period might be considered late if: It’s been

more than 38 days since your last period

. You’re normally really regular, and your period is more than three days late.

Why is my period late if I’m not pregnant?


Extreme weight loss, hormonal irregularities, and menopause

are among the most common causes if you’re not pregnant. You may miss a period for one or two months, or you may experience complete amenorrhea—that is, no period for three or more months in a row.

How late can a period be without being pregnant?

Some people have their period every 28 days like clockwork. But most people will experience a late or missed period

at least once

without being pregnant, and that’s perfectly normal.

Carlos Perez
Author
Carlos Perez
Carlos Perez is an education expert and teacher with over 20 years of experience working with youth. He holds a degree in education and has taught in both public and private schools, as well as in community-based organizations. Carlos is passionate about empowering young people and helping them reach their full potential through education and mentorship.