Avoid eating grapefruit or drinking grapefruit juice while you are taking sirolimus
. Also, you should preferably take sirolimus at least one hour before eating. If you do take it with food, you should take it each time with food to avoid changes in sirolimus levels.
What happens if you drink grapefruit juice with blood pressure medicine?
They’re used as part of the treatment of conditions such as high blood pressure (hypertension) and coronary heart disease. Grapefruit juice interacts with some calcium channel blockers and
increases the level of the medicine in
your blood.
Does grapefruit juice affect hydrochlorothiazide?
Grapefruit juice can
significantly increase the blood levels
and effects of medications like felodipine. You may be more likely to experience side effects such as headache, low blood pressure, irregular heartbeat, swelling, and fluid retention.
What medications should not be taken with grapefruit?
Examples of common medications that interact with grapefruit juice include certain
statin cholesterol
drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).
What can you not take with hydrochlorothiazide?
- Barbiturates. If you take these drugs with hydrochlorothiazide, your blood pressure may be lowered too much. …
- Lithium. …
- Blood pressure drugs. …
- Cholesterol-lowering drugs. …
- Corticosteroids. …
- Diabetes drugs. …
- Narcotics. …
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
Is grapefruit bad for high blood pressure?
Grapefruit contains compounds that may interfere with how your body absorbs some drugs, including some blood pressure medicines.
It can leave too much or too little of the drug in your bloodstream
, which may be dangerous. Always ask your doctor or pharmacist if grapefruit could affect the medicine you’re taking.
What are the side effects of eating grapefruit?
It showed that grapefruit can increase these drugs’ effects, resulting in
excessive drowsiness
( 12 ). Eating grapefruit while taking the mood-related medications above can result in heart rhythm changes, excessive sleepiness, and other drug-specific effects.
Which medicines should not be taken together?
- Dangerous duo: Tylenol and multi-symptom cold medicines. …
- Dangerous duo: Any combo of ibuprofen, naproxen, and aspirin. …
- Dangerous duo: Antihistamines and motion-sickness medications. …
- Dangerous duo: Anti-diarrheal medicine and calcium supplements. …
- Dangerous duo: St.
Should you drink more water when taking hydrochlorothiazide?
Be careful not to become overheated or dehydrated in hot weather while taking hydrochlorothiazide.
Talk to your doctor
about how much fluid you should be drinking; in some cases drinking too much fluid is just as harmful as not drinking enough fluids.
Can I drink coffee while taking hydrochlorothiazide?
Taking caffeine with water pills might cause potassium levels to drop too low. Some “water pills” that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide), and others.
Is hydrochlorothiazide hard on your kidneys?
Hydrochlorothiazide can aggravate kidney dysfunction
and is used with caution in patients with kidney disease. Hydrochlorothiazide can lower blood potassium, sodium, and magnesium levels.
Why can’t you eat grapefruit with some medications?
Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice
can block the action of intestinal CYP3A4
, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body.
Can grapefruit clear plaque in arteries?
In one study, animals fed a high-cholesterol diet plus grapefruit pectin had 24
percent
narrowing of their arteries, versus the control with 45 percent narrowing. In other words, the pectin binds to cholesterol and helps to remove arterial buildup.
What happens if you eat grapefruit everyday?
Regularly consuming grapefruit is thought to
improve heart health by reducing risk factors for heart disease
, such as high blood pressure and cholesterol. In one study, people who ate grapefruit three times daily for six weeks experienced significant reductions in blood pressure over the course of the study.
