GENERALLY AVOID: Grapefruit juice
may increase the plasma concentrations of oxycodone
.
Should you avoid grapefruit with oxycodone?
Mixing the prescription painkiller oxycodone with grapefruit can
cause serious breathing problems
, and adding the fruit to a dose of the popular statin simvastatin, or Zocor, can lead to rhabdomyolysis, a breakdown of muscle fibers that can lead to kidney damage.
Can I eat grapefruit while taking Percocet?
Avoid eating grapefruit
or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine.
Does grapefruit interfere with pain medication?
Yes
. Grapefruit and certain other citrus fruits, such as Seville oranges, can interfere with several kinds of prescription medications. Don’t take these interactions lightly.
What prescription drugs should not be taken with grapefruit?
Examples of common medications that interact with grapefruit juice include certain
statin cholesterol
drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor
What happens if you take grapefruit with oxycodone?
Mixing the prescription painkiller oxycodone with grapefruit can cause serious breathing problems, and adding the fruit to a dose of the popular statin simvastatin, or Zocor, can lead to
rhabdomyolysis
, a breakdown of muscle fibers that can lead to kidney damage.
What happens if I drink grapefruit juice with oxycodone?
The Nordic Pharmacology Society reported grapefruit juice
can increase exposure to oral oxycodone
. Through biochemical processes, the juice can actually increase the concentration of oxycodone in the body and enhance its effects. In many cases, the interaction can be harmful.
Does grapefruit interfere with opioids?
Discussion: Grapefruit juice is known to be an inhibitor of the CYP3A4 isoenzyme. Various studies demonstrate that through CYP3A4 inhibition, grapefruit juice increases serum levels of opioids, such as methadone, though
no clinically significant effects have been reported
.
Can you eat grapefruit with cholesterol medication?
Do not drink grapefruit juice if you
‘re taking simvastatin. Grapefruit juice increases the level of simvastatin in your blood and makes side effects more likely. Atorvastatin interacts with grapefruit juice if you drink large quantities (more than 1.2 litres daily), but an occasional glass is thought to be safe.
What blood pressure meds should not be taken with grapefruit?
- Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin).
- Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).
Can I eat grapefruit in the morning and take Lipitor at night?
How much grapefruit is okay when taking statins like Lipitor? To be on the safe side, many researchers suggest
you avoid consuming grapefruit entirely when taking statins such as Lipitor
.
What fruit should be avoided if an individual is taking a statin medication?
Grapefruit
and statins: Eating grapefruit, either the fruit itself or as juice, can slow the body’s ability to metabolize statin cholesterol-lowering drugs, which include Lipitor, Crestor and Zocor.
Is grapefruit bad for high blood pressure?
Grapefruit contains compounds that may interfere with how your body absorbs some drugs, including some blood pressure medicines.
It can leave too much or too little of the drug in your bloodstream
, which may be dangerous. Always ask your doctor or pharmacist if grapefruit could affect the medicine you’re taking.
Does grapefruit enhance hydrocodone?
GENERALLY AVOID:
Grapefruit juice may increase the plasma concentrations of hydrocodone
. The proposed mechanism is inhibition of CYP450 3A4-mediated metabolism of hydrocodone by certain compounds present in grapefruit.
Does grapefruit juice make Viagra work better?
Conclusions: Grapefruit juice
increases sildenafil bioavailability and tends to delay sildenafil absorption
. Sildenafil pharmacokinetics may become less predictable with grapefruit juice.
How long should you wait to eat grapefruit after taking medication?
This makes it more likely that you will have side effects from the medicine. Interactions can happen
up to three days
after eating or drinking grapefruit. This means you cannot drink grapefruit juice in the morning and take your medications later in the day to stop possible medicine interactions.
