Do ACE Inhibitors Cause Depression?

by | Last updated on January 24, 2024

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Do ACE inhibitors cause depression? Diuretics, calcium channel blockers, and angiotensin converting enzyme (ACE) inhibitors

appear to have the lowest association with depression

and are therefore the drugs of choice when depression is a risk. Physicians should know which drugs introduce the risk of causing or worsening depression.

Contents hide

Do ACE inhibitors affect mood?

Bottom line: ACE inhibitors and angiotensin II receptor antagonists are associated with low rates of neuropsychiatrie side effects, though

mood symptoms, psychosis, and delirium have been reported

.

Do ACE inhibitors make you depressed?

9 Drugs Types That May Cause Depression

The following kinds of medications are among those that

may lead to depression

: 1. Beta-blockers and ACE inhibitors (blood pressure drugs): metoprolol, atenolol, enalapril, and quinapril.

Can blood pressure meds make you depressed?

What is the most troublesome side effect of ACE inhibitors?


Angioedema (swelling under the skin)

Angioedema is the most severe symptom associated with ACE inhibitors and occurs in 0.1-0.2% of patients. Airway swelling and obstruction due to the accumulation of fluid (and bradykinin) are the main features of angioedema.

Do ACE inhibitors cause anxiety?

Lisinopril (lisinipril)

can cause nausea, headaches, anxiety, insomnia, drowsiness, nasal congestion and sexual dysfunction

. Lisinopril (lisinipril) should be stopped if there are symptoms or signs of an allergic reaction including feelings of swelling of the face, lips, tongue or throat.

Which hypertension medications cause depression?

With reference to diuretics, except for the NoAntiHTN group, all antihypertensive treatments were significantly associated with higher risk of depression:

beta blockers (OR 1.53, 95% CI 1.22–1.91), calcium channel blockers (OR 1.40, 95% CI 1.12–1.75) and angiotensin antagonists (OR 1.30, 95% CI 1.04–1.63)

(Figure 5).

What medications can make you depressed?

  • Acne medications.
  • Pain relievers.
  • Allergy medications.
  • Thyroid medications.
  • Antibiotics.

Can blood pressure medication cause anxiety and depression?

Although previous research hinted there might be a connection between high blood pressure medications and depression,

a new study of dozens of commonly used drugs found no such link

. In fact, the Danish researchers found the opposite — nine blood pressure drugs were associated with a lower risk of depression.

Can lisinopril cause anxiety and depression?


Anxiety is a possible side effect of lisinopril

.

Which antidepressant should be avoided with hypertension?

Examples of antidepressants that can raise your blood pressure are:

Monoamine oxidase inhibitors

. Tricyclic antidepressants. Fluoxetine (Prozac, Sarafem)

Which antidepressant is best for high blood pressure?

The norepinephrine reuptake inhibitor

reboxetine

is considered a safe option because of its neutral effects on blood pressure in long-term studies, even if both hypotensive and hypertensive effects are reported.

Which blood pressure meds cause anxiety?


Reserpine

is used to treat high blood pressure and certain emotional conditions, as well as a few other problems. Side effects may include dizziness, faintness, anxiety, and palpitations. Some individuals have even developed phobic reactions while taking reserpine.

How long can you stay on ACE inhibitors?

There is therefore sufficient evidence to state that long-term ACE-inhibitor therapy for

up to 5 years

provides a continuous, cumulative benefit in patients with post-infarction heart failure or LV dysfunction.

Can you just stop taking ACE inhibitor?


You should not stop taking the lisinopril suddenly without your doctors permission

– you could risk experiencing rebound hypertension, which is a sudden increase in blood pressure in response to stopping or reducing hypertension medications.

Who should not take ACE inhibitors?

  • Pregnant women. …
  • People with severe kidney failure. …
  • People who have ever had a severe allergic reaction that caused their tongue and lips to swell, even if it was from a bee sting, should not take ACE inhibitors.

Are ACE inhibitors good for anxiety?

The finding suggests that ACE (angiotensin converting enzyme) inhibitors or ARBs (angiotensin receptor blockers)

could be valuable tools for treating or preventing post-traumatic stress disorder

. The results were published online May 1 in the Journal of Clinical Psychiatry.

Can lisinopril be used for depression?


The ACE inhibitor lisinopril had greater penetration into the brain and a more rapid antidepressant effect

. The behavioral depression was also associated with reduced serum and mPFC availability of bradykinin (which is pro-inflammatory among other functions), but captopril increased its serum and mPFC availability.

Does high blood pressure make you emotional?

Can you take antidepressants with blood pressure medication?

Blood Pressure Management


Many people with high blood pressure are able to use the most common antidepressants with no problems, but some may require adjustments to their high blood pressure treatment program

.

Which is used in controlling depression and hypertension?


Equanil

is an important tranquillizer used in depression and hypertension.

What medications cause depression in elderly?

Drugs That May Cause Depression

Elderly people are particularly at risk.

Isotretinoin (Claravis, Sotret

): This drug treats severe acne. Anticonvulsants: Anticonvulsants are used to control epileptic seizures, examples include ethosuximide (Zarontin) and methsuximide (Celontin).

Which drugs can cause mental illness?


Stimulant drugs

can make you feel depressed, anxious and paranoid. Cocaine – a type of stimulant – can make previous mental health problems recur and trigger psychosis and schizophrenia. Ecstasy users can experience memory problems. Hallucinogenic drugs such as magic mushrooms can make any mental health issues worse.

Which drugs cause mood swings?

  • benzodiazepines (a group of anti-anxiety drugs)
  • stimulants, such as Adderall and Ritalin.
  • sleeping medication.
  • antidepressants.

Can statins cause depression?

Psychiatric adverse effects, altering mood, personality, and behavior, sometimes arise in patients receiving statins.

Statin psychiatric effects can include irritability/aggression, anxiety or depressed mood

, violent ideation, sleep problems including nightmares, and possibly suicide attempt and completion.

Is there an antidepressant that lowers blood pressure?


Citalopram, Escitalopram, and Paroxetine

In a geriatric population of patients, citalopram was effective in further reducing BP when depressed and hypertensive subjects were treated with amlodipine (75).

Can high blood pressure meds make you irritable?

According to the study’s findings,

calcium antagonists and beta blockers are associated with a two-fold increased risk for mood disorders

, while angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers decrease mood disorder risk.

What is the most common side effect of lisinopril?

The most common side effects in people taking lisinopril for high blood pressure are

dry cough, dizziness, and headache

. People taking lisinopril for heart failure or heart attack tend to experience low blood pressure, fainting, and kidney problems as the most common side effects.

What medication can replace lisinopril?

Is lisinopril good for anxiety?


Lowering of BP is associated with reduced anxiety-like behavior in DSS

, which indicate the connection of cardiovascular disorder and cognitive function in adult hypertensive DSS. Whether Lisinopril has an additional direct effect on brain functions in DSS rats will be further studied.

Can low serotonin cause high blood pressure?

Serotonin has complex effects on the cardiovascular system.

In the intact animal it may cause increases or decreases of blood pressure

and in isolated blood vessels contraction or relaxation depending on the species and vascular bed studied, the route of administration and the dosage used.

Does blood pressure medication lower anxiety?

Does anxiety elevate blood pressure?

Anxiety doesn’t cause long-term high blood pressure (hypertension). But

episodes of anxiety can cause dramatic, temporary spikes in blood pressure

.

Does lisinopril affect mood?


Anxiety is a possible side effect of lisinopril

.

What medications can cause anger?

Drug classes most commonly associated with aggressive ADRs are

anti-epileptic drugs, antidepres- sants, immunomodulatory drugs, and benzodiazepines

.

Can beta-blockers change your personality?


Researchers have suspected beta-blockers of having negative psychological side effects, including depression, anxiety, drowsiness, insomnia, hallucinations and nightmares.

Rebecca Patel
Author
Rebecca Patel
Rebecca is a beauty and style expert with over 10 years of experience in the industry. She is a licensed esthetician and has worked with top brands in the beauty industry. Rebecca is passionate about helping people feel confident and beautiful in their own skin, and she uses her expertise to create informative and helpful content that educates readers on the latest trends and techniques in the beauty world.