While gender affirming hormone therapy usually results in an improvement in mood,
some people may experience mood swings or a worsening of anxiety, depression, or other mental health conditions
as a result of the shifts associated with starting a second puberty.
Does TRT improve mental health?
TRT effectively improved total serum testosterone levels as well as IIEF-5, AMS, and BDI scores in men with TDS, suggesting that
TRT may indeed improve some aspects of depression and cognitive ability
in such patients.
Does testosterone help with anxiety?
1
Administration of testosterone, a steroid hormone, has been shown to reduce socially fearful, avoidant, and submissive behavior
. Indeed, in general, men have half the reported rate of anxiety disorders as women; this may be partially due to the role of testosterone in levels of anxiety.
Does testosterone change your mind?
Brain imaging shows that testosterone therapy given as part of sex reassignment
changes the brain structures and the pathway associated with speech and verbal fluency
. This result supports research that women in general may deal with speech and interaction differently than men.
Does testosterone affect mental health?
Testosterone and your mental health
When you have lower-than-normal testosterone levels, these receptors are, quite literally, left high and dry, which can lead to:
Mood swings
. Irritability. Stress.
Does low testosterone cause anxiety and panic?
Depression, anxiety, irritability, and other mood changes are common in men and women with low T. However,
researchers aren’t sure what causes the correlation
. Testosterone therapy can boost the mood of many people with low T, particularly older adults.
Does testosterone relieve depression?
Findings This systematic review and meta-analysis of 27 randomized placebo-controlled clinical trials involving a total of 1890 men found that
testosterone treatment was associated with a significant reduction of depressive symptoms
, particularly in participants who received higher-dosage regimens.
Does low testosterone cause mental problems?
Low testosterone can change your mood and may lead to symptoms of depression, anxiety, or other mental health conditions
. More than 16 million Americans suffer from depression. This mental illness is considered by the World Health Organization to be one of the leading causes of poor health and disability worldwide.
Can taking testosterone make you depressed?
Social research suggests
high androgen levels cause aggressive behavior in men and women and as a consequence may cause depression
. Higher androgen values are more pronounced at young ages and before and after delivery of a baby and might be responsible for the “baby blues”.
Does testosterone help with anxiety and depression?
A decrease in serotonin activity in the brain is linked to feelings of depression. Testosterone may play a role in serotonin reuptake in the brain, improving its activity and your overall mood. Researchers also theorize that
testosterone may have anti-anxiety activity
.
Can testosterone make anxiety worse?
The results of a study published in the Journal of Affective Disorders suggest that
higher serum total testosterone in men and androstenedione in young men may increase the risk for anxiety disorders
.
Can I take testosterone while on antidepressants?
About 20% of men have sexual problems because they’re taking an antidepressant.
Combining an antidepressant with testosterone therapy may improve sexual function
.
Does testosterone increase serotonin?
Now, the study led by Rupert Lanzenberger from the University Department of Psychiatry and Psychotherapy has demonstrated for the first time worldwide that
testosterone increases the number of serotonin transporters (proteins) in the human brain
.
Can testosterone injections cause personality changes?
Many people report that they are frustrated, angry, and irritable for no reason. Depending on the dose of T you are receiving,
it can also create feelings of depression and wild mood swings
. In severe cases, the mental side effects of testosterone include the destabilization of bipolar or schizoaffective disorder.
Does testosterone make you smarter?
Abstract. The relationship between serum total testosterone (T) level and fluid intelligence (Cattell’s Culture Fair Intelligence Test) was studied in young men and women.
There was no significant difference between IQs of men and women
. IQ tended to increase with T in men, except at very high T levels.
Can low testosterone cause suicidal thoughts?
Low testosterone levels may be associated with suicidal behavior in older men
while high testosterone levels may be related to suicidal behavior in adolescents and young adults: a hypothesis. Int J Adolesc Med Health.
Is low testosterone linked to depression?
3, 2004 —
Low testosterone levels may cause clinical depression in older men
, a new study shows. Age related decreases in the male sex hormone testosterone are common in older men; some 30% of men over age 55 have it. Low levels of the hormone can cause symptoms of fatigue, a decreased sex drive, and irritability.
Testosterone is known to have an anxiety-suppressing effect and facilitates contact in social situations
. Participants with social anxiety disorder who received testosterone avoid eye contact less often than when they received a placebo, the researchers reported in the journal Psychoneuroendocrinology.
Can low testosterone cause foggy brain?
Low Testosterone and Cognition
Men with low testosterone commonly experience cognitive issues, often described as “brain fog.”
For example, you might realize that it’s difficult to focus or think clearly, or you might have a harder time remembering things.
