Conclusions: Plasma concentration of montelukast was higher when administered with grapefruit juice, as compared to with water. This may have been due to the
effect of grapefruit on liver metabolism of montelukast
and the cytochrome P450 system.
Can you eat grapefruit with Singulair?
Yes
. Sadly, grapefruit juice and actual grapefruit can interfere with the way your body deals with dozens of medications—even if you don’t drink the juice and take the pills at the same time.
Does montelukast interact with grapefruit?
The results of this study demonstrated reduced montelukast metabolism with grapefruit juice, and increased drug serum levels. It may be appropriate to advise patients taking montelukast for allergic airway disease not to drink grapefruit juice simultaneously.
What can you not take with montelukast?
What should I avoid while taking montelukast?
Avoid situations or activities that may trigger an asthma attack
. If your asthma symptoms get worse when you take aspirin, avoid taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) while you are taking montelukast.
What medications should not be taken with grapefruit?
Examples of common medications that interact with grapefruit juice include certain
statin cholesterol
drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).
Is montelukast anti inflammatory?
Anti-inflammatory properties of montelukast, a leukotriene receptor antagonist
How good is montelukast?
Montelukast has an
average rating of 6.1 out of 10
from a total of 99 ratings for the treatment of Asthma, Maintenance. 52% of reviewers reported a positive effect, while 38% reported a negative effect.
Can you just stop taking montelukast?
Montelukast controls the symptoms of asthma and allergic rhinitis but does not cure these conditions. Continue to take montelukast even if you feel well.
Do not stop taking montelukast without talking to your doctor
.
Does montelukast raise blood pressure?
Does montelukast cause weight gain or increased blood pressure?
It shouldn’t
. In clinical studies, montelukast oral tablets weren’t reported to cause weight gain or increased blood pressure. Steroid treatments for asthma, such as prednisone, may cause weight gain or increased blood pressure.
How safe is montelukast?
60 Montelukast is generally safe and well tolerated
; headache and gastrointestinal symptoms are the most commonly reported side effects. 57 Other side effects include hypersensitivity reactions, sleep disorders, drowsiness, increased bleeding tendency, hallucination, and possible mood changes and suicidal thoughts.
How long should you wait to eat grapefruit after taking medication?
This makes it more likely that you will have side effects from the medicine. Interactions can happen
up to three days
after eating or drinking grapefruit. This means you cannot drink grapefruit juice in the morning and take your medications later in the day to stop possible medicine interactions.
Why can’t you eat grapefruit with sertraline?
Anti-anxiety medications such as sertraline (Zoloft), buspirone (Buspar), and diazepam (Valium) can
cause drowsiness
or dizziness when taken with grapefruit juice.
Why is grapefruit bad for high blood pressure?
Grapefruit contains compounds that may interfere with how your body absorbs some drugs
, including some blood pressure medicines. It can leave too much or too little of the drug in your bloodstream, which may be dangerous. Always ask your doctor or pharmacist if grapefruit could affect the medicine you’re taking.
How many days should montelukast be taken?
Dosage. Most people take montelukast
once a day in the evening
to prevent asthma or allergy symptoms. However, if exercise makes your asthma worse, your doctor might tell you to take montelukast 2 hours before you exercise. Never take more than 1 dose a day.
What are the side effects of taking montelukast?
Common side effects of montelukast include
upper respiratory infection, fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, and sinus infection
.
Does montelukast help with post nasal drip?
Montelukast is a cysteinyl leukotriene antagonist, which also
reduces sputum and blood eosinophils
.
