Does Grapefruit Juice Affect Hydrochlorothiazide?

by | Last updated on January 24, 2024

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Does grapefruit juice affect hydrochlorothiazide?

Grapefruit juice can significantly increase the blood levels and effects of medications like felodipine

. You may be more likely to experience side effects such as headache, low blood pressure, irregular heartbeat, swelling, and fluid retention.

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Can I eat grapefruit while taking lisinopril hydrochlorothiazide?

ACE-inhibitors like enalapril, captopril, lisinopril and ramipril

have not shown any interaction with grapefruit juice

although such an interaction might be possible with angiotensin II type 1 receptor antagonists like losartan and valsartan [18].

Can you eat grapefruit while taking a diuretic?


Do not use grapefruit juice to mix this medication

. Some mixtures of medications can lead to serious and even fatal consequences.

Can you drink grapefruit juice with high blood pressure medication?

Which blood pressure medications should not be taken with grapefruit?

  • High cholesterol: atorvastatin (one brand: Lipitor) and simvastatin (one brand: Zocor)
  • High blood pressure: felodipine (one brand: Plendil), nifedipine (one brand: Procardia), and nisoldipine (one brand: Sular)

What fruits interfere with high blood pressure medication?

People taking ACE inhibitors or ARBs should limit their intake of high-potassium foods like

bananas, oranges, avocados, tomatoes, white and sweet potatoes and dried fruits —, especially apricots

.

Does grapefruit lower blood pressure quickly?

Citrus fruits


Studies have also shown drinking orange and grapefruit juice may help reduce blood pressure

. Yet, grapefruit and grapefruit juice can interfere with common blood-pressure-lowering medications, so consult your healthcare provider before adding this fruit to your diet ( 4 , 6 ).

Does grapefruit affect blood pressure?

Studies have shown that

eating grapefruit every day can lower systolic blood pressure by as much as five points

. This may be due to grapefruit’s high levels of potassium, which neutralize the negative effects of sodium (a common cause of hypertension).

What foods interfere with blood pressure medication?

  • Bananas. Don’t eat them if you take ACE inhibitors such as captopril, enalapril and fosinopril among others. …
  • Grapefruit. …
  • Milk. …
  • Black liquorice. …
  • Kale and other leafy greens. …
  • Air-dried sausages or aged cheese. …
  • Coffee. …
  • Alcohol.

Do bananas interfere with blood pressure medication?

However, eating too many potassium-rich foods like bananas, oranges and green, leafy vegetables

can be problematic if a person is taking ACE inhibitors or angiotensin receptor blockers (ARBs)

. Designed to lower blood pressure, these medications also reduce potassium excretion via urination.

What medication is affected by grapefruit?

Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).

Why should you avoid grapefruit while taking certain medications?


Grapefruit interferes with proteins in the small intestine and liver that normally break down many medications

. Eating grapefruit or drinking grapefruit juice while taking these medications can lead to higher levels of them in your blood — and more side effects.

How much grapefruit juice can you drink a day?

The fruit is better than the juice

Grapefruit juice can also spike your blood sugar more than the fruit itself. If you opt for juice of any kind, Delbridge recommends

not drinking more than 6 ounces a day

and going only for 100% juice products that don’t have added sugar.

Can you take vitamins with hydrochlorothiazide?

Interactions between your drugs


No interactions were found between Daily Multiple Vitamins and hydrochlorothiazide

. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

What are the side effects from hydrochlorothiazide?

  • Back, leg, or stomach pains.
  • black, tarry stools.
  • blistering, peeling, or loosening of the skin.
  • bloating.
  • blood in the urine or stools.
  • blue lips and fingernails.
  • chest pain or tightness.
  • clay-colored stools.

What drinks should I avoid with high blood pressure?

Drinking more than 4 cups of coffee a day may increase your blood pressure. If you’re a big fan of

coffee, tea or other caffeine-rich drinks, such as cola and some energy drinks

, consider cutting down.

How long does it take for grapefruit to lower your blood pressure?

“In the present study, a single intake of grapefruit juice increased the plasma concentration of nifedipine and also decreased blood pressures

3 hours

after intake of grapefruit juice…”

Does drinking lemon water help lower blood pressure?

How can I lower my blood pressure instantly in an emergency?

What time of day is blood pressure highest?

Usually, blood pressure starts to rise a few hours before a person wakes up. It continues to rise during the day,

peaking in midday

. Blood pressure typically drops in the late afternoon and evening. Blood pressure is usually lower at night while sleeping.

How can I lower my blood pressure immediately?

  1. Take a warm bath or shower. Stay in your shower or bath for at least 15 minutes and enjoy the warm water. …
  2. Do a breathing exercise. …
  3. Relax!

What juice is good for high blood pressure?

A 2020 review reported that drinking

cranberry or cherry juice

may improve your blood pressure. Another review published in Nature in 2016 found that consuming berries lowered both systolic blood pressure and LDL cholesterol.

Can I take my blood pressure medicine with orange juice?

Can drinking lots of water lower blood pressure?

Something as simple as

keeping yourself hydrated by drinking six to eight glasses of water every day improves blood pressure

. Water makes up 73% of the human heart,1 so no other liquid is better at controlling blood pressure.

Is it better to take blood pressure medicine in the morning or the evening?

New research suggests that

taking your blood pressure medication at bedtime may more effectively reduce your risk of illness or death due to heart and blood vessel disease

. Timing of medication is important because blood pressure follows a daily rhythm. It rises higher during the day and falls at night when we sleep.

Does coffee raise blood pressure?


Caffeine may cause a short, but dramatic increase in your blood pressure, even if you don’t have high blood pressure

. It’s unclear what causes this spike in blood pressure. The blood pressure response to caffeine differs from person to person.

Is grapefruit hard on kidneys?

How long does grapefruit juice stay in your system?

The interaction potential of even high amounts of grapefruit juice with CYP3A4 substrates dissipates within

3 to 7 days

after ingestion of the last dose of grapefruit juice.

What vitamins should not be taken with grapefruit?

What happens if I drink grapefruit juice everyday?

Is Ocean Spray Ruby red grapefruit juice Good for You?

Our Diet Ruby Red grapefruit juice drink is

an excellent source of Vitamin C

and only contains 1 gram of sugar per serving. It’s a great way to support your immune system daily.

What brand of grapefruit juice is the healthiest?

What should you avoid when taking hydrochlorothiazide?

  1. Barbiturates. If you take these drugs with hydrochlorothiazide, your blood pressure may be lowered too much. …
  2. Lithium. …
  3. Blood pressure drugs. …
  4. Cholesterol-lowering drugs. …
  5. Corticosteroids. …
  6. Diabetes drugs. …
  7. Narcotics. …
  8. Nonsteroidal anti-inflammatory drugs (NSAIDs)

Can I take vitamin D with hydrochlorothiazide?

While further research may be required, this study suggests that, for the majority of HCTZ users,

combined HCTZ use with higher doses of vitamin D (2000 IU to 4000 IU) appears safe with a low rate of clinically significant hypercalcemia

.

Should you drink a lot of water when taking hydrochlorothiazide?

Severe sweating, diarrhea, or vomiting can increase the risk for dehydration. Report prolonged diarrhea or vomiting to your doctor. To prevent dehydration,

drink plenty of fluids unless your doctor directs you otherwise

. If you have diabetes, hydrochlorothiazide may affect your blood sugar.

What happens when you eat grapefruit while taking lisinopril?

Grapefruit interferes with proteins in the small intestine and liver that normally break down many medications. Eating grapefruit or drinking grapefruit juice while taking these medications

can lead to higher levels of them in your blood

— and more side effects.

Sophia Kim
Author
Sophia Kim
Sophia Kim is a food writer with a passion for cooking and entertaining. She has worked in various restaurants and catering companies, and has written for several food publications. Sophia's expertise in cooking and entertaining will help you create memorable meals and events.