Two months after starting treatment with Lupron (leuprolide) Depot for endometriosis,
most women (98%) will stop having periods
. In studies, 2% of women reported light bleeding or spotting. Most women will resume their normal periods within 3 months after treatment with Lupron Depot has ended.
Can you ovulate while on Lupron?
Ovulation cannot occur naturally while on Lupron
because LH, which triggers ovulation, is suppressed. This prevents a premature surge of the LH before the retrieval, which could cause loss of the cycle. Once the eggs are mature, an injection of Human chorionic gonadotropin (hCG) or LH is given to stimulate ovulation.
How long after Lupron do you ovulate?
Depending on the medication you’re taking, it may take anywhere from
four to six weeks (with nasal spray agonists) or six to ten weeks (with injections)
for your fertility to return. You should not rely on GnRH agonists to absolutely prevent ovulation.
Does Lupron affect fertility?
For ovulation induction,
Lupron reduces the interference of the pituitary gland with the development of eggs when gonadotropins (FSH/HMG) are administered
. Most women will have a better response to gonadotropins (higher estrogen levels and more eggs) with the simultaneous use of Lupron.
How long does it take for Lupron to stop periods?
Lupron lowers estrogen levels in the body, typically triggering menopause-like symptoms. According to the manufacturer’s clinical trials, 74% of participants who took Lupron stopped having their periods after the first month of treatment, and menstruation ceased in 98% of this group after
2 months
.
How long does it take for Lupron to wear off?
When do the effects of Leuprolide acetate go away? The effects of Leuprolide acetate will decrease after you stop taking the medicine. If you’ve been getting Lupron® every 3 months, your period will usually return within
4 to 8 months
after your last shot.
Does Lupron affect egg quality?
Lupron will not trigger egg maturation if used earlier
since it would prevent the artificially timed production of a LH surge, which is required for the eggs to mature. Hence, Lupron can effectively trigger maturation only if the antagonist is used earlier during the IVF stimulation.
Can I get pregnant while on Lupron?
Yes, you may still become pregnant if you are using Lupron Depot
. Lupron Depot is not a method of birth control. Even though you may not have a period, unprotected intercourse could result in pregnancy.
What happens when Lupron wears off?
If Lupron treatment is stopped,
testosterone levels can rise and your cancer may worsen
. Do not discontinue Lupron Depot unless your doctor tells you to stop treatment. In men, testosterone is reduced to castrate concentrations with Lupron Depot treatment.
Why does Lupron trigger IVF?
Some women do not respond well to the long protocol using leuprolide. They do not make enough follicles to give a good chance for pregnancy from IVF with this regimen.
The LH surge that is initiated in response to the Lupron injection is short-lived. The LH surge will adequately induce maturation of the eggs for IVF
.
Does Lupron make your period lighter?
Two months after starting treatment with Lupron (leuprolide) Depot for endometriosis, most women (98%) will stop having periods. In studies,
2% of women reported light bleeding or spotting
.
Do you gain weight on Lupron?
Weight changes may occur with Lupron Depot use.
One of the most common side effects of women taking Lupron Depot is weight gain
. However, some women may experience weight loss instead.
