Does Methotrexate Interfere With Antibiotics?

by | Last updated on January 24, 2024

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can be taken with other .

You should not take methotrexate

while taking antibiotics containing trimethoprim-sulfa (Bactrim®, Sulfatrim®, etc…). If you are prescribed one of these medications for an infection, do not take your methotrexate that week.

What antibiotics can you take with methotrexate?

This is because combining the 2 medications can cause a range of unpleasant and sometimes serious side effects. However,

some forms of penicillin, such as amoxicillin

, can be used in combination with methotrexate. You may experience a skin rash if you take penicillin and allopurinol, which is used to treat gout.

Can you take Augmentin while taking methotrexate?


Do not take Augmentin® while you

are taking probenecid or methotrexate without telling your doctor. Probenecid may increase the levels of Augmentin® in your body. Augmentin® may increase the levels of methotrexate in your body.

Is it OK to take amoxicillin with methotrexate?

methotrexate amoxicillin


Talk to your doctor before using methotrexate together with amoxicillin

. Medications like amoxicillin, especially when given at high dosages for serious infections, can sometimes increase the blood levels and effects of methotrexate.

What medications Cannot be taken with methotrexate?

  • Aspirin (Zorprin, Excedrin)
  • Bromfenac (Prolensa, Bromday)
  • Etodolac (Lodine)
  • Fenoprofen (Nalfon)
  • Ibuprofen (Advil, Motrin)
  • Naproxen (Aleve, Naprosyn)
  • Magnesium salicylate (Doan's)
  • Salsalate.

Can I take vitamin D with methotrexate?


No interactions were found

between methotrexate and Vitamin D3. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Why should you not touch methotrexate?

Even touching or inhaling the

dust from the tablet can allow the medicine to get into the body

. Methotrexate goes into sperm, so it's important that a man taking it doesn't get his partner pregnant. Whether you're male or female, you must use birth control while taking methotrexate.

What happens if you take methotrexate and folic acid on the same day?

You may hear people suggest that you skip taking folic acid the same day that you take your methotrexate, but the jury is out on the benefit of doing this. “There are studies suggesting

no decrease in

the efficacy of MTX if taken the same day as folic acid, but the same may not be true for folinic acid.

How long do you stay on methotrexate?

If you are taking methotrexate to treat rheumatoid arthritis, it may take 3 to 6 weeks for your symptoms to begin to improve, and

12 weeks

or longer for you to feel the full benefit of methotrexate. Continue to take methotrexate even if you feel well. Do not stop taking methotrexate without talking to your doctor.

What to avoid while on antibiotics?

  • Grapefruit — You should avoid both the fruit and the juice of this sour citrus product. …
  • Excess Calcium — Some studies show that excess calcium interferes with absorption. …
  • Alcohol — Mixing alcohol and antibiotics can lead to a host of unpleasant side effects.

What should you not take with amoxicillin?

  • allopurinol (may increase the incidence of rash)
  • anticoagulants (blood thinners), such as warfarin (may prolong bleeding time)
  • oral contraceptives (may decrease absorption leading to reduced efficacy)

Can I drink coffee while taking antibiotics?

Antibiotics (Quinolone antibiotics) interacts with COFFEE

Some antibiotics might decrease how quickly the body breaks down caffeine. Taking these antibiotics along with coffee can increase the

risk of side effects

including jitteriness, headache, increased heart rate, and other side effects.

Can I drink tea while taking antibiotics?

In almost every case and for all types of antibiotics they tested, the researchers found that drinking

green tea

at the same time as taking the antibiotics appeared to increase the action of the antibiotics and reduce drug resistance in bacteria. In certain cases, even low concentrations of green tea were effective.

What foods should you avoid when taking methotrexate?


There are no specific foods

that you need to avoid while taking methotrexate. However, methotrexate may reduce your ability to fight infection. Therefore, it's best to avoid unpasteurised milk and soft cheeses.

Is weight gain a side effect of methotrexate?

Official Answer.

Methotrexate was shown to cause a modest amount of weight gain over 6 months

, in a study measuring weight changes in people with rheumatoid arthritis. The patients who were most likely to gain weight when starting methotrexate, were patients who had recently lost weight due to rheumatoid arthritis.

Does methotrexate shorten your life?

Methotrexate (MTX) can reduce disease activity and radiologic progression, but

little is known about its effect on mortality

.

Sophia Kim
Author
Sophia Kim
Sophia Kim is a food writer with a passion for cooking and entertaining. She has worked in various restaurants and catering companies, and has written for several food publications. Sophia's expertise in cooking and entertaining will help you create memorable meals and events.