Long-term use of a particular anticholinergic drug may increase subsequent risk for developing
dementia
. The use of oxybutynin, solifenacin, and tolterodine for overactive bladder (OAB) was tied to an increased risk for dementia in patients with diabetes, according to a paper published in the PLoS One journal.
What class of drug is tolterodine?
Tolterodine is in a class of medications called
antimuscarinics
. It works by relaxing the bladder muscles preventing bladder contraction.
Is tolterodine an anticholinergic?
Tolterodine tartrate is marketed as a
bladder-selective anticholinergic drug
that is reported to be free of significant cognitive adverse effects.
Can you take tolterodine long-term?
It was concluded that tolterodine is well tolerated and maintains its clinical efficacy during
9 months of treatment
. The high proportion of patients remaining on treatment indicates that tolterodine is an effective long-term treatment for overactive bladder.
Does tolterodine cause memory loss?
Darifenacin and tolterodine stand out as having
been shown to not cause impairment of memory
or other cognitive functions in randomised clinical trials.
How long can you take tolterodine?
Do not take tolterodine for longer than you need to. Your doctor will check every
6 to 12 months
that your treatment is still needed.
What medications should be avoided when taking tolterodine?
Some products that may interact with this drug include: anticholinergic drugs (such as
atropine
, scopolamine), other antispasmodic drugs (such as dicyclomine, propantheline), certain anti-Parkinson’s drugs (such as trihexyphenidyl), belladonna alkaloids, potassium tablets/capsules, pramlintide.
What is the best time to take tolterodine?
You can take tolterodine
either before or after meals
. Swallow your doses with a drink of water. Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly.
What is the best medicine for overactive bladder?
Medications that relax the bladder can be helpful for relieving symptoms of overactive bladder and reducing episodes of urge incontinence. These drugs include:
Tolterodine (Detrol) Oxybutynin
, which can be taken as a pill (Ditropan XL) or used as a skin patch (Oxytrol) or gel (Gelnique)
Can you drink alcohol with tolterodine?
Alcohol may increase drowsiness and dizziness while
you are taking tolterodine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination.
What happens if you take too much tolterodine?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include dry mouth, blurred vision
, and fast heartbeat.
Can tolterodine cause joint pain?
constipation or diarrhea; stomach pain or upset; joint pain; or. headache.
Does tolterodine cause water retention?
General. The most common adverse events reported were dry mouth, headache, constipation, vertigo/dizziness, and abdominal pain. Dry mouth, constipation, abnormal vision (accommodation abnormalities), urinary retention, and xerophthalmia are expected side effects of antimuscarinic agents.
What foods to avoid if you have an overactive bladder?
- carbonated beverages, such as sparkling water.
- caffeinated beverages, such as coffee and tea.
- chocolate.
- alcoholic drinks.
- sports drinks, such as Gatorade.
- citrus fruit.
- tomatoes and tomato-based products, including ketchup, tomato sauce, and chili.
- spicy foods.
What is the number one food that fights dementia?
What is the number one food that fights dementia?
Green leafy vegetables
are probably the number one food that fights dementia. They have a strong, positive effect on cognitive health.
Does oxytrol cause dementia?
It found that oxybutynin treatment was
associated with a 2.3-fold increased risk of dementia in people
with diabetes compared to those who did not take this class of medication [2].
