Clostridium perfringens was first discovered by William H. Welch, MD, in
1891
at The Johns Hopkins Hospital after an autopsy on a 38-year-old man and was initially named Bacillus aerogenes capsulatus.
Where did Clostridium perfringens originate?
Common sources of C. perfringens infection include
meat, poultry, gravies, and other foods cooked in large batches and held at an unsafe temperature
. Outbreaks tend to happen in places that serve large groups of people, such as hospitals, school cafeterias, prisons, and nursing homes, and at events with catered food.
What is Clostridium perfringens nickname?
Clostridium perfringens (formerly known as
C. welchii, or Bacillus welchii
) is a Gram-positive, rod-shaped, anaerobic, spore-forming pathogenic bacterium of the genus Clostridium.
How many people died from Clostridium perfringens?
Characteristic C. perfingens, n (%) Other etiologies, n (%) | Diarrhea 8,980 (91) 94,031 (84) | Abdominal cramps 6,989 (73) 70,308 (69) | Vomiting 1,328 (14) 62,849 (58) |
---|
When was the last Clostridium perfringens outbreak?
Clostridium perfringens Foodborne Outbreak during an Athletic Event in Northern Greece,
June 2019
.
What kills Clostridium perfringens?
The Organism: Clostridium perfringens are anaerobic bacteria that can produce spores. The bacteria can exist as a vegetative cell or in the dormant spore form in food.
Thorough cooking (140°F)
will kill the vegetative cells, but spores may survive.
Is Clostridium perfringens contagious to humans?
C. perfringens
is not spread person-to-person
.
Is Clostridium perfringens fatal?
Clostridium perfringens is an underrecognized but common cause of foodborne illness that usually causes self-limited disease and
rarely is fatal
.
How does Clostridium perfringens affect the body?
Stomach effects:
Loss of appetite, nausea, vomiting, and watery or bloody diarrhea with crampy stomach pain
. Respiratory effects: Difficulty in breathing, wheezing and coughing. Mouth and throat pain with some blood in the saliva and sputum may be possible.
What antibiotics treat Clostridium perfringens?
Any number of antibiotics can be used to remove Clostridium perfringens. Some choices include:
ampicillin, amoxicillin, metronidazole, erythromycin, and tylosin
. Tetracycline was formerly on the list but too much resistance has developed.
What diseases are caused by Clostridium perfringens?
perfringens is also known to cause other diseases, such as infections of the skin and deeper tissues. This is known as “
clostridial myonecrosis”
or “gas gangrene” and also results from toxins produced by C.
How can Clostridium be prevented?
- Practice good hand hygiene.
- Regularly clean areas of your home that may become contaminated with Clostridium difficile.
- Practice good hand hygiene.
- Cleaning surfaces, spills, and accidents.
- Exclusion Policies.
Which disease is caused by Clostridium?
Clostridium perfringens bacteria are one of the most common causes of
foodborne illness (food poisoning)
. CDC estimates these bacteria cause nearly 1 million illnesses in the United States every year. C. perfringens can be found on raw meat and poultry, in the intestines of animals, and in the environment.
What is unique about Clostridium perfringens?
Clostridium perfringens is a Gram-positive, anaerobic, rod-shaped bacterium from the Clostridium genus. It is both
heat-resistant and cold-tolerant
, surviving in conditions with little or no oxygen.
How does Clostridium perfringens spread?
How is Clostridium perfringens spread? The Clostridium perfringens toxin
must be swallowed to cause disease
. This usually happens when someone eats food that has been stored at the wrong temperature after cooking. Clostridium perfringens is found in the stool (feces) of infected people.
How do you get rid of Clostridium bacteria?
- Vancomycin (Vancocin): A doctor may prescribe 125 milligrams (mg) to be taken by mouth four times a day for 10 days.
- Fidaxomicin (Dificid): This is a new antibiotic that works similarly to vancomycin. …
- Metronidazole (Flagyl): A person would take 500 mg, three times a day for 10 days, by mouth.