Fatal overdoses of duloxetine have been reported with as little as 1,000 milligrams . Overdoses generally manifest with sleepiness, coma, serotonin syndrome, seizures, tachycardia, hyper or hypotension, and vomiting. Treatment should be supportive.
What is the highest amount of Cymbalta you can take?
Adults—40 milligrams (mg) per day (given as 20 mg two times per day) to 60 mg per day (given either once a day or as 30 mg two times per day). Your doctor may increase your dose as needed. However, the dose is usually not more than 120 mg per day .
How many mg of Cymbalta is too much?
Typical starting dosage: 30–60 mg per day. Typical maintenance dosage: Total daily dose of 40 mg (given as 20-mg doses twice daily) or 60 mg (given either once daily or as 30-mg doses twice daily). Maximum dosage: 120 mg per day .
Is Cymbalta hard on your heart?
Blood pressure and heart rate: Cymbalta may cause an increase in blood pressure and/or rapid heart rate . If you have been diagnosed with high blood pressure or other types of heart disease, caution is recommended. Inform your doctor of your entire heart health history before taking this drug.
Is it safe to take 120 mg of Cymbalta?
In adults ages 65 years and older, it’s recommended to start Cymbalta at a dose of 30 mg once a day. This dose should be continued for 2 weeks. After that, the dose can be increased to 60 mg/day. The maximum dosage of Cymbalta for treating anxiety in adults of any age is 120 mg per day.
How do I wean off Cymbalta 60 mg?
Taper schedule: The main way to manage Cymbalta discontinuation syndrome
Is 30 mg of Cymbalta effective?
For some patients, it may be desirable to start at 30 mg once daily for 1 week , to allow patients to adjust to CYMBALTA before increasing to 60 mg once daily. While a 120 mg/day dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer any additional benefits.
Why is Cymbalta bad for you?
Chemicals from Cymbalta may cause liver damage . In some cases, this has been fatal. Symptoms may include itching, right upper abdominal pain, dark urine, yellow skin or eyes, enlarged liver and increased liver enzymes. Cymbalta may cause enlarged liver and increased liver enzymes.
What are the dangers of taking Cymbalta?
Nausea, headache and a dry mouth are among the most common side effects of Cymbalta. In rare cases, patients have suffered serious — and sometimes fatal — side effects, including liver damage, abnormal bleeding, and suicidal thoughts and behaviors.
Is Cymbalta hard on the liver?
“Postmarketing reports of liver injury (including hepatitis and cholestatic jaundice) suggest that patients with pre-existing liver disease who take [Cymbalta] may have an increased risk for further liver damage ,” says the FDA.
Should I take Cymbalta at night?
Can I take Cymbalta (duloxetine) at night? It is best to take Cymbalta (duloxetine) at the same time every day . Most people take it in the morning, but if you find that you feel drowsy after taking it in the morning, try taking it in the evening.
Is Duloxetine a strong antidepressant?
Duloxetine is an antidepressant medicine . It’s used to treat depression and anxiety. It’s also used to treat nerve pain, such as fibromyalgia, and can be used to treat stress urinary incontinence in women. Duloxetine comes as capsules and is only available on prescription.
Can I drink coffee with Cymbalta?
Caffeine may increase the blood levels and effects of DULoxetine. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.
What does Cymbalta withdrawal feel like?
Missing doses of duloxetine may increase your risk for relapse in your symptoms. Stopping duloxetine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).
Can I take Cymbalta every other day?
It is possible but unlikely that you will get any benefit from this low dose. If you do not have problems with side-effects, increase the dose to 60 mg once a day. Duloxetine can be taken any time of the day with or without a meal .
Does Cymbalta cause brain fog?
A lack of short-term memory, difficulty in concentrating, and brain zaps are just some of the complaints experienced by people taking Cymbalta.
