Propofol is dosed at
1.5 to 4 mg per pound (3 to 8 mg/kg) intravenous
, given slowly over 1 minute.
How do you give a dog propofol?
Administer by
intravenous injection only
. INDUCTION OF GENERAL ANESTHESIA: For induction, propofol injection should be titrated against the response of the patient over 30-60 seconds or until clinical signs show the onset of anesthesia.
Can propofol be used on dogs?
Propofol can be used for sedation, induction of anesthesia, and maintenance of anesthesia in small animal patients
. In all these situations recovery from its effects is typically rapid and smooth.
How do you calculate propofol?
Most patients will require
0.5 – 1 mg propofol/kg body weight
over 1 to 5 minutes for onset of sedation. Maintenance of sedation may be accomplished by titrating Propofol to the desired level of sedation. Most patients will require 1.5 – 4.5 mg propofol/kg body weight/h.
Is there a weight limit for anesthesia?
Most operating tables are designed for patients of up to 120–140 kg in weight
. For those who weigh more than this limit, specially designed tables may be needed. Position should be maintained to prevent nerve compressions and pressure sores.
How much Propofol is lethal?
Propofol Related Deaths Blood Level of Propofol ( μg/mL ) | Accidental Deaths | 26 year old male ICU nurse, known propofol abuser 5.3 |
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How do you measure propofol in dogs?
Dosing Information of Propofol for Dogs and Cats
Propofol is dosed at
1.5 to 4 mg per pound (3 to 8 mg/kg) intravenous, given slowly over 1 minute
. For constant infusion, propofol is dosed at 0.05 to 0.3 mg per pound per minute (0.1 to 0.6 mg/kg/min).
Is propofol safe for older dogs?
Propofol may be considered the first choice for anesthetic induction in most geriatric dogs and cats
.
How long does it take for propofol to wear off in a dog?
Vomiting may also occur. In terms of how long does dog anesthesia take to wear off completely, the typical time span is
between 24 and 48 hours
. During this time, your dog may continue to seem drowsy or low energy.
What are the side effects of propofol in animals?
Conclusions:
Respiratory depression and apnea
are the most likely adverse effects induced by i.v. administration of propofol to dogs. Propofol administered i.v. at a rate of 20 mg/kg/10 s induces minimal cardiovascular depression at dosages in excess of the apneic dosage.
What drug do vets use to sedate dogs for surgery?
Acepromazine maleate
(brand names and alternative names: acetylpromazine, ACE, ACP, PromAce®) is a sedative/tranquilizer used as a pre-anesthetic and for chemical restraint in dogs and cats.
Is Buprenorphine safe for dogs?
Buprenorphine should be used cautiously in pets with low thyroid levels, liver disease, bile disease, heart and/or lung disease, kidney disease, Addison’s disease, or in very young, very old, or debilitated pets. It should be used with extreme caution in pets with head trauma or other nervous system dysfunction.
How much does propofol cost?
Group Drug / Comparator Price ($) | Benzodiazepines Midazolam $5.8 / vial $126.3 / vial | Lorazepam $12.42 / vial | Propofol $9.2 / vial $23.0 / vial $46.0/ vial | hr=hour, IM = intramuscular; IV = intravenous |
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How much Propofol is in general anesthesia?
For general anesthesia, anesthesiologists use a large “bolus” of
between 100 and 200 milligrams
of propofol to put patients under and then a continuous infusion of much smaller amounts (in the micrograms per minute, with the exact amount depending on the person’s weight) to keep patients under.
How much propofol can you bolus?
Most patients require an infusion of 25 mcg/kg/min to 75 mcg/kg/min (1.5 mg/kg/h to 4.5 mg/kg/h) or incremental bolus doses of
10 mg or 20 mg
. In Elderly, Debilitated, Neurosurgical, or ASA-PS III or IV Patients: Most patients require 80% of the usual adult dose.
How do they determine how much anesthesia to give?
Among the things the anesthesiologist measures or observes, and uses to guide the type and amount of anesthetic given are:
heart rate and rhythm, blood pressure, breathing rate or pattern, oxygen and carbon dioxide levels, and exhaled anesthetic concentration
.
How much does anesthesia cost per pound?
The established FDA recommendations are
3.2 mg/lb
, with an absolute maximum of 500 mg per appointment. When using these values for the same hypothetical patient, the result is significantly different: a maximum of 13 cartridges of the local anesthetic drug (23.4 ml; 468 mg) may be administered.
How do they wake you up from propofol?
Propofol sedation is nothing at all like sleep. Sleep is reversible with external stimulation –
if you shake somebody
, they wake up.
How much Propofol is used for endoscopy?
Conclusion. In conclusion, a propofol infusion rate of
1000 ml/h
appears to be the most appropriate rate for upper gastrointestinal endoscopy anesthesia. This rate resulted in fewer complications and adverse reactions during endoscopy, as well as in improved endoscopist satisfaction.
What drug did Michael Jackson Take that killed?
On June 25, 2009, American singer Michael Jackson died of acute
propofol and benzodiazepine
intoxication at his home on North Carolwood Drive in the Holmby Hills neighborhood of Los Angeles, California.
How long does propofol last once opened?
The opened vial should be placed in a covered container, held at room temperature and used within the allotted
28 day
timeframe. Refrigeration is not recommended. Any unused propofol remaining at the end of 28 days should be discarded.
Can propofol be be reused?
In our study,
16% admitted to using the same propofol syringe for different patients and 21% to reusing 50 ml syringes for propofol infusions
. Of these, 30% reuse extension tubing between patients. Thus it appears that little change in clinical practice has occurred since publication of the SASA Guidelines.
Should propofol be refrigerated?
Propofol is provided in a soybean oil and lecithin emulsion and should be handled with strict aseptic technique. The manufacturer states that propofol
should not be refrigerated
and, once opened, the contents should be used within 6 hours because of the high potential for significant bacterial contamination.
Can you put a 12 year old dog under anesthesia?
Not surprisingly, older dogs are increasingly vulnerable to diseases that may require anesthesia as part of the treatment process. Due to the natural physiological deterioration that occurs with age, experts estimate that
the risk of anesthetic death increases as much as seven times for dogs older than 12 years of age
.
How much is it to put a dog under anesthesia?
The cost of anesthesia for dogs can fall anywhere
between $90 and $1,200
depending on your pet’s size and health condition, as well as the type of procedure they undergo. Some vets charge by the hour or half-hour, whereas other procedures are priced by weight because larger dogs need a larger dose of sedative drugs.
Is a 14 year old dog too old for surgery?
The answer may not be what you’d expect. Age is not a disease, and
your dog is never “too old” to receive the quality care he or she needs, even if it requires anesthesia and surgery.