Results: It was found that patients receiving amlodipine in the combination antihypertensive therapy had
insomnia manifestations much less frequently
as compared to indapamide. A statically significant decrease in blood pressure (BP) and a higher proportion of patients with target BP were observed in both groups.
Can blood pressure meds cause insomnia?
Anti-arrhythmic drugs used to treat heart rhythm problems can cause insomnia and other sleep difficulties.
Beta blockers
, used for high blood pressure, arrhythmias, and angina, increase the chance of insomnia, awakenings at night, and nightmares.
Does amlodipine cause sleep problems?
The more common side effects that can occur with amlodipine include:
swelling of your legs or ankles
.
tiredness or extreme sleepiness
.
What are the side effects of amlodipine?
The most common side effects include
headache, flushing, feeling tired and swollen ankles
. These usually improve after a few days. Amlodipine can be called amlodipine besilate, amlodipine maleate or amlodipine mesilate.
Is it OK to take amlodipine at night?
It does not matter what time of day you take amlodipine (morning or evening) but
it is best to take it at the same time every day
, when you are most likely to remember, for more even blood levels and therefore effectiveness.
When should you not take amlodipine?
Do not take this medicine if it has been
more than 12 hours since you missed your last dose
.
What foods should I avoid when taking amlodipine?
Do not eat or drink lots
of grapefruit or grapefruit juice
. This is because grapefruit can increase the concentration of amlodipine in your body and worsen side effects.
Should you stop taking amlodipine If your ankles swell?
In those taking higher dose (10mg) amlodipine, about 10 people in every 100 reported leg swelling (10%). Interestingly, women are more likely to get the swelling, and most people tolerate this well and
do not have to discontinue the medication
.
What are the long term effects of amlodipine?
If it continues for a long time, the heart and arteries may not function properly. This can
damage the blood vessels of the brain, heart, and kidneys
, resulting in a stroke, heart failure, or kidney failure.
What is the safest blood pressure medication with the least side effects?
While the class of blood pressure-lowering medicines called angiotensin-converting enzyme (ACE) inhibitors may be prescribed more commonly,
angiotensin receptor blockers (ARBs)
work just as well and may cause fewer side effects.
How many days does it take for amlodipine to work?
Amlodipine starts to work on the day you start taking it, but
it may take a couple of weeks for full effect
. If you’re taking amlodipine for high blood pressure, you may not have any symptoms. In these cases, you may not feel any different when you take amlodipine.
Why is amlodipine given at night?
New research suggests that taking your blood pressure medication at bedtime
may more effectively reduce your risk of illness
or death due to heart and blood vessel disease. Timing of medication is important because blood pressure follows a daily rhythm. It rises higher during the day and falls at night when we sleep.
How much does 5mg amlodipine lower BP?
Titration of amlodipine from 5 to 10 mg daily in patients not responding to treatment with the 5 mg dose resulted in a statistically significant decrease in blood pressure: systolic blood pressure by −12.4 mm Hg (SE = 0.53) and diastolic blood pressure by
−7.2 mm Hg
(SE = 0.32) (both P < 0.0001; Figure 3).
What should I do if my blood pressure is 160 over 100?
If your blood pressure is higher than 160/100 mmHg, then
three visits are enough
. If your blood pressure is higher than 140/90 mmHg, then five visits are needed before a diagnosis can be made. If either your systolic or diastolic blood pressure stays high, then the diagnosis of hypertension can be made.
Is it safe to take 10mg of amlodipine?
Adults—5 to 10 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However,
the dose is usually not more than 10 mg per day
.
Why is amlodipine banned in Canada?
The affected medication may contain traces of N-nitrosodimethylamine (NDMA), a “probable human carcinogen” that could increase the
risk of cancer
through long-term exposure above acceptable levels, Health Canada says.
