Does Grapefruit Affect Montelukast?

Does Grapefruit Affect Montelukast? Conclusions: Plasma concentration of montelukast was higher when administered with grapefruit juice, as compared to with water. This may have been due to the effect of grapefruit on liver metabolism of montelukast and the cytochrome P450 system. Can you eat grapefruit with Singulair? Yes. Sadly, grapefruit juice and actual grapefruit can