Can You Take Benadryl And Ibuprofen Together?

Can You Take Benadryl And Ibuprofen Together? Can you take Benadryl and ibuprofen together? In general, it is safe to combine Benadryl with over-the-counter pain medicines such as ibuprofen or Tylenol. All of these medicines work in different ways. Is it safe to take Benadryl with ibuprofen? Interactions between your drugs No interactions were found