Why Does Amiodarone Cause Hypotension?

Why Does Amiodarone Cause Hypotension? In the acute setting, amiodarone can cause hypotension due to vasodilation and depression of myocardial contractility; this may be partly due to the solvent, polysorbate 80 or benzyl alcohol, used to assist in dissolving the drug [6–8]. Can amiodarone cause low blood pressure? In addition to being an antiarrhythmic medication,