What Is The Cause Of Melanosis Coli?

What Is The Cause Of Melanosis Coli? What causes melanosis coli? Melanosis coli usually results from chronic use of laxatives of the anthranoid group. Some examples of anthranoid laxatives are senna (sennosides; Senocot, Senokot EXTRA and others) and rhubarb derivatives. Many of these laxatives have been in use for hundreds of years. Is Melanosis coli