Is It OK To Take Hydrocodone And Buspirone Together?

Is It OK To Take Hydrocodone And Buspirone Together? If hydrocodone is used with buspirone, the dose of one or both drugs should be reduced. (Moderate) The combination of buspirone and other CNS depressants, such as sedating h1-blockers, can increase the risk for sedation. What medications interact with buspirone? Abilify (aripiprazole) Adderall (amphetamine / dextroamphetamine)