How Do Antibiotics That Are Members Of The Quinolone Family Kill Bacteria?

How Do Antibiotics That Are Members Of The Quinolone Family Kill Bacteria? They exert their actions by inhibiting bacterial nucleic acid synthesis through disrupting the enzymes topoisomerase IV and DNA gyrase, and by causing breakage of bacterial chromosomes. However, bacteria have acquired resistance to quinolones, similar to other antibacterial agents, due to the overuse of