bicarbonate loss

Does Diarrhea Lead To Alkalosis Or Acidosis? Diarrhea typically causes hypovolemia, hypokalemia, hyperchloremia, and metabolic acidosis. Does diarrhea cause metabolic acidosis? Hyperchloremic acidosis is caused by the loss of too much sodium bicarbonate from the body, which can happen with severe diarrhea. Does diarrhea cause metabolic alkalosis or acidosis? Diarrhea is the most common cause