How Is Bilirubin Metabolized?
How Is Bilirubin Metabolized? Conjugated bilirubin is excreted from the hepatocyte into the bile canaliculus by an active transport mechanism. Excretion into bile is the rate-limiting step in bilirubin metabolism. … This recycled urobilinogen may be re-excreted into the bile by the liver or into urine by the kidney. How does the liver metabolize bilirubin?