Does Biotin Have Any Contraindications?

Does Biotin Have Any Contraindications? There are no evident contraindications to taking this vitamin. Biotin is a safe and nontoxic vitamin that the body excretes when in excess. There are no known herbal interactions with biotin. What medications should not be taken with biotin? carbamazepine; phenobarbital; phenytoin; or. primidone. Does biotin conflict with any medications?