How Can I Rebuild My Bladder Lining?

How Can I Rebuild My Bladder Lining? Pentosan polysulfate sodium is the only FDA-approved oral medication for interstitial cystitis. The drug binds to the walls of the bladder, helping replace and repair the lining. Symptom improvement can take up to six months, but several studies have shown moderately positive results. Can bladder lining be repaired?