Can You Take Medicine Anally?

Can You Take Medicine Anally? Though there are a limited number of commercially available drugs specifically manufactured for rectal administration Can you take pain killers rectally? Any opioid, including oxycodone, codeine, and buprenorphine, may be compounded for rectal administration (see Administering Rectal Analgesics, at right), and morphine, methadone, hydromorphone, and oxymorphone are commercially available as