How Does The Choroid Plexus Form The Blood Brain Barrier? The blood-cerebrospinal fluid (CSF) barrier is formed by tight junctions between neighboring choroid plexus epithelial cells—halting the paracellular movement of molecules both into, and out of, the brain. Additional chemical barriers exist to impede movement of molecules into the central nervous system. What is the
What Can Pass Through Blood-brain Barrier? Only water, certain gases (e.g. oxygen), and lipid-soluble substances can easily diffuse across the barrier (other necessary substances like glucose can be actively transported across the blood-brain barrier with some effort). What substances are transported through the blood-brain barrier? Glucose from blood enters the brain by a transport protein.
Can Proteins Travel Across Teh Bbb? Most proteins in the plasma are not able to cross the blood—brain barrier because of their size and hydrophilicity. Consequently, concentrations of plasma proteins in the brain are very low (Table 32-1). Can amino acids cross the BBB? In the absence of paracellular diffusion, polar solutes, such as amino