Is Sprue The Same As Celiac Disease?

Is Sprue The Same As Celiac Disease? Celiac disease, sometimes called celiac sprue or gluten-sensitive enteropathy, is an immune reaction to eating gluten, a protein found in wheat, barley and rye. Is celiac sprue an autoimmune disease? Celiac sprue (CS) is a unique autoimmune disorder caused by sensitivity to gluten and characterized by enteropathy. CS